Over-the-Counter Oral Contraceptives
This JAMA Insights in the Women’s Health series discusses the first over-the-counter progestin-only oral contraceptive available in the US, including its effectiveness, mechanism of action, and accessibility.
Medical Knowledge
Autonomic Neural Blockade in Minimally Invasive Surgery
This article discusses the use of intraoperative autonomic neural blockade as a technique to manage postoperative visceral pain and symptoms of postoperative nausea and vomiting in minimally invasive surgery.
Peristomal Erosion in a Man With Crohn Disease
A man in his 50s with a 10-year history of Crohn disease had intermittent bowel obstructions leading to total proctocolectomy and ileostomy, and 5 weeks after surgery he developed a painful, erosive lesion around his stoma on the anterior abdominal…
Restrictive vs Liberal Transfusion Strategy in Patients With Acute Brain Injury – The TRAIN Randomized Clinical Trial
Importance Blood transfusions are commonly administered to patients with acute brain injury. The optimal hemoglobin transfusion threshold is uncertain in this patient population. Objective To assess the impact on neurological outcome of 2 different hemoglobin thresholds to guide red blood cell transfusions…
Ventricular Septal Rupture After ST-Segment Elevation Myocardial Infarction
This case report describes a diagnosis of ventricular septal rupture in a patient in his 70s after ST-segment elevation myocardial infarction (STEMI) due to right coronary artery occlusion.
Endometrial Cancer Classification and Management in the Molecular Subtyping Era
A 65-year-old woman presented with a 6-month history of postmenopausal vaginal bleeding, and endometrial biopsy showed grade 2 endometrioid adenocarcinoma. What would you do next?
Patient With Painful and Destructive Nasal Mass
A patient in their mid-30s presented with pain and swelling involving the bridge of their nose. What is your diagnosis?
Measure Accurately: In-Office BP Best Practices
Accurate blood pressure (BP) measurement is a crucial aspect of patient care, as it informs diagnosis, treatment, and management of hypertension and other cardiovascular conditions. However, the skill itself can be prone to errors, which can lead to misdiagnosis and…
Measure Accurately: Self-Measured BP Best Practices
Self-Measured Blood Pressure (SMBP) is a valuable tool for managing hypertension and improving patient outcomes, but its effectiveness relies on health care professionals being able to train patients on how to obtain and document accurate measurements. To address this challenge,…
Preexposure Prophylaxis (PrEP) for HIV
This JAMA Insights discusses the expanding PrEP options for preventing HIV, including the considerations for initiation and follow-up and implementation challenges of these medications.
