Importance Dalbavancin is a long-acting intravenous lipoglycopeptide that may be effective for treatment of complicated Staphylococcus aureus bacteremia without requiring long-term intravenous access. Objective To evaluate the efficacy and safety of dalbavancin vs standard therapy for completion of treatment of complicated S aureus bacteremia. Design, Setting,…
This JAMA Insights discusses transmission, clinical presentation, and diagnosis of measles and emphasizes the importance of vaccination to protect those at highest risk for complications from measles, including young children and pregnant individuals.
A woman in her early 50s presented with a neck mass, incidentally discovered during evaluation of recurrent headaches. What is your diagnosis?
Importance Mental health challenges among physicians represent a critical public health issue with profound implications for health care delivery and workforce sustainability. Despite the proven effectiveness of mental health treatment in improving outcomes, most physicians with mental health conditions do not…
Importance As childhood cancer survival improves worldwide, supporting the growing survivor population, who are at increased risk of morbidity and mortality compared with the general population, is critical. No prior publications have summarized the landscape of childhood cancer survivorship research globally…
Importance The Latina, Latino, Latinx, Latine, Hispanic, or of Spanish Origin (LHS+) population is 20% of the US population and experiences disparities in health care access and quality. The common mission of medical schools is to prepare future health care practitioners…
This Clinical Insights discusses the role primary care clinicians have in screening, diagnostic testing, and treatment of patients with obstructive sleep apnea.
This case report describes a patient in their 70s with treatment-resistant polymyositis, coronary artery disease, bare-metal stent placement, 3 months of fatigue, and worsening proximal muscle weakness.
Importance Hemorrhoidal disease, pathology of the tissue lining of the anal canal, affects approximately 10 million individuals in the US. Hemorrhoidal disease may impair quality of life due to bleeding, pain, anal irritation, and tissue prolapse. Observations Hemorrhoids are classified as internal,…
Importance Chronic rhinosinusitis with nasal polyps causes severe symptoms and impaired quality of life. Stapokibart is a novel monoclonal antibody that targets interleukin 4Rα. Objective To assess the efficacy and safety of stapokibart as an add-on treatment to intranasal corticosteroids in patients…
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