Unprecedented In Vivo MRI Resolution of Basal Ganglia at 11.7 T
This case report describes 11.7-T in vivo human brain magnetic resonance imaging (MRI) of the basal ganglia in 2 healthy volunteers.
Medical Knowledge
Management of Colon and Rectal Injuries From Blunt and Penetrating Trauma – Evidence-Based Recommendations From the World Society of Emergency Surgery
Importance Traumatic colon and rectal injuries generate wide practice variation across diagnosis, operative strategy, technical conduct, and perioperative care. Management has shifted from mandatory fecal diversion toward selective primary repair and physiology-guided reconstruction, but decision-making remains inconsistent. Objective To develop…
Best Practices for Managing Pseudofolliculitis Barbae – An Expert Consensus Delphi Study
Importance Pseudofolliculitis barbae (PFB) is a chronic inflammatory disease caused by penetration of a shaved, curved hair shaft into the skin. Standardized recommendations for diagnosing and managing PFB are needed. Objective To establish expert consensus recommendations outlining best practices for…
Medicolegal Evaluations for Asylum Seekers
This JAMA Insights discusses the importance of medicolegal evaluations for those seeking asylum and encourages clinicians to complete additional training to conduct these evaluations.
Elephantiasic Pretibial Myxedema
This case report describes a man with enlargement of the lower legs with pink nodules and malodor.
Chemotherapy and Surgical Outcomes for Ovarian Metastases From Colorectal Cancer – A Narrative Review
Importance Colorectal cancer is the third most common and deadly cancer among women worldwide. Although ovarian metastases from colon cancer are relatively uncommon, they remain clinically significant due to their association with poor prognosis and the longstanding suspicion that the…
Macular Hole Following Nd:YAG Laser Vitreolysis for Floaters
This case report of a 31-year-old woman who underwent Nd:YAG laser vitreolysis for floaters describes the postoperative development of a macular hole and its treatment.
Odynophagia With a Glottic Mass and Diffuse Lymphadenopathy
A 34-year-old man with no significant medical history presented with progressive dysphonia, dysphagia, and an infiltrative laryngeal mass that remained nondiagnostic on multiple biopsies. What was the diagnosis?
Patents on Small-Molecule Drugs Approved by the US Food and Drug Administration, 1990-2019
Importance Patent protection allows pharmaceutical companies to charge high prices for prescription drugs during periods of market exclusivity, and their expiration usually defines when generic competitors can enter the US market. Patents on drug active ingredients are classified as primary…
MRI Characteristics of Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease – A Review
Importance Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is a demyelinating disease distinct from multiple sclerosis (MS) and aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder (AQP4+NMOSD). Magnetic resonance imaging (MRI) is central to confirming attacks, defining lesion distribution, and excluding alternative diagnoses…
