Hypooleon and Hyperoleon After Retinal Detachment Repair
This case report describes a diagnosis of inverted hyperoleon in a patient who underwent retinal detachment repair using high-molecular-weight silicone oil.
Medical Knowledge
Corneal Toxicity Associated With Mirvetuximab
This case report discusses a diagnosis of corneal toxicity in a woman aged 74 years who presented with bilateral decreased visual acuity after receiving mirvetuximab infusions for metastatic ovarian cancer.
Public Health Implications of Legal Challenges to the FDA’s Regulation of Laboratory-Developed Tests
Importance Laboratory-developed tests (LDTs) refer to in vitro diagnostics developed and used by individual laboratories. LDTs are widely used in modern medicine, with their results informing over 70% of clinical decisions. The US Food and Drug Administration (FDA) has historically claimed…
Iris Ganglion Cell
This case report discusses the finding of a ganglion cell in the iris of an adult patient who underwent enucleation for uveal melanoma.
Postvaccinal Meningoencephalitis With Radial Perivascular Enhancement
This case report describes an atypical postvaccinal encephalitis in a 60-year-old man, with radial perivascular enhancement consistent with inflammation of glial fibrillary acidic proteinñrich white matter loci.
T1-Weighted Spin Echo Sequence and Encephalitis
This case report highlights brain imaging of 2 patients with a disease course suggestive of autoimmune glial fibrillary acidic protein astrocytopathy.
Inhaled Pharmacotherapy for Stable COPD
This JAMA Clinical Guidelines Synopsis summarizes the 2025 Global Strategy for the Diagnosis, Management, and Prevention of COPD.
New Frontier, New Challenges—Recognizing and Managing Adverse Effects of Antiamyloid Therapies
This clinical insight discusses the diagnosis and management of adverse effects of antiamyloid therapies and what medications require consideration or avoidance.
Diagnosis and Treatment of Type 2 Diabetes in Adults – A Review
Importance Type 2 diabetes involves progressive loss of insulin secretion from pancreatic β cells in the setting of insulin resistance and manifests clinically as hyperglycemia. Type 2 diabetes accounts for 90% to 95% of all cases of diabetes globally, with estimates…
AMA STEPSFORWARD – Mastering AI Governance – Key STEPS for Success
Dr Srinivasan Suresh, CIO, CMIO, and VP of UPMC Children’s Hospital of Pittsburgh, discusses how they approach augmented intelligence (AI) governance at their organization.
