Importance Generalized pustular psoriasis (GPP) lacks internationally accepted definitions and diagnostic criteria, impeding timely diagnosis and treatment and hindering cross-regional clinical and epidemiological study comparisons. Objective To develop an international consensus definition and diagnostic criteria for GPP using the modified Delphi method….
Clinical Question What is the efficacy of pharmacologic interventions in preventing proliferative vitreoretinopathy? Bottom Line There is limited high-quality evidence to support currently available pharmacological options for prevention of proliferative vitreoretinopathy.
Importance Identification of individuals at high risk for atherosclerotic cardiovascular disease within the population is important to inform primary prevention strategies. Objective To evaluate the prognostic value of routinely available cardiovascular biomarkers when added to established risk factors. Design, Setting, and Participants Individual-level…
One in three pregnant patients run the risk of experiencing uterine tachysystole (UT) during labor augmentation or induction with oxytocin. Reducing UT diagnosis-to-treatment time can avert adverse patient outcomes and decrease the risk of an obstetric malpractice claim. This two-part…
One in three pregnant patients run the risk of experiencing uterine tachysystole (UT) during labor augmentation or induction with oxytocin. Reducing UT diagnosis-to-treatment time can avert adverse patient outcomes and decrease the risk of an obstetric malpractice claim. This two-part…
Researchers have identified more than 100 biases that can interfere with diagnostic reasoning. These biases can sway practitioners’ thinking during both intuitive and deliberative cognitive processes. This activity discusses biases and offers strategies to reduce their detrimental impacts.
Fetal malpresentation is defined as a fetus presenting at birth in a non-vertex presentation as either occiput transverse (OT) or occiput posterior (OP). This condition occurs 15% to 25% at term and 5% to 12% at birth, frequently increases risk…
Importance Most people who smoke do not quit on their initial attempt. Objective To determine the best subsequent strategy for nonabstinence following initial treatment with varenicline or combined nicotine replacement therapy (CNRT). Design, Setting, and Participants Using a double-blind, placebo-controlled, sequential multiple assignment…
Antimicrobial resistance (AMR) is a looming pandemic whose poor health outcomes are unlikely to be equitably distributed. This article focuses on intersections between AMR and inequities in health care workplaces in the United States and identifies the following as key…
Despite mounting attention in recent years, health threats posed by antimicrobial resistance are not new. Antimicrobial resistance has dogged infectious disease treatment processes since the first modern antimicrobials were discovered.
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