The Harms of Inappropriate Food-Specific Immunoglobulin E TestingóLess Is More
This Teachable Moment describes a 56-year-old woman with a concern for a food allergy and bilateral leg muscle spasms.
Medical Knowledge
A Direct-to-Patient Digital Health Program for Lung Cancer Screening – A Randomized Clinical Trial
Importance Screening chest computed tomography (CT) scans reduce lung cancer mortality in high-risk individuals, but less than 20% of eligible individuals are screened in the US. Objective To determine whether a direct-to-patient digital health program increases lung cancer screening. Design, Setting, and…
Lung Cancer in Nonsmoking Individuals – A Review
Lung cancer in nonsmoking individuals (defined as people who have smoked fewer than 100 cigarettes in their lifetime) accounts for 15% to 20% of all lung cancer cases worldwide. In the US, the annual incidence of lung cancer in nonsmoking…
Ambulate TID or Hospital-Acquired Disability (HAD)?
Why is it that individuals who are hospitalized often leave the hospital with decreased mobility and functional abilities? In this episode of Clinically Significantô, host Maylyn Martinez, MD, MSc explores the causes, diagnosis, and treatment of Hospital-acquired disability (HAD). Are…
Can AI Help Physicians Detect Sepsis?
Sepsis: at its inception, it is difficult to recognize but easy to treat; left unattended, it becomes easy to recognize and difficult to treat. As the adage states, sepsis is notoriously difficult to recognize in its early stages, due to…
Whole Child, Whole Health – Lessons Learned for Behavioral Health Integration in Pediatrics
Dr. Marian Earls, board-certified General and Developmental and Behavioral Pediatrician, and Chair of the AAP Mental Health Leadership Work Group for the American Academy of Pediatrics (AAP) discusses key learnings the AAP has garnered as a long-standing member of the…
Postpartum Hemorrhage
This JAMA Insights discusses risk factors for, assessment, and management of postpartum hemorrhage.
Pemphigus Foliaceous With Secondary Herpes Simplex Infection
This case report describes a woman in her 40s with bilateral periorbital erythema, sharply demarcated pitted erosions, and dizziness and headache who was diagnosed with pemphigus foliaceus.
American Society of Breast Surgeons and Society of Breast Imaging 2025 Guidelines for the Management of Benign Breast Fibroepithelial Lesions
Importance Many patients are diagnosed with benign breast lesions; however, evidence- and consensus-based guidelines for the management of benign breast disease (BBD) are limited. Observations The American Society of Breast Surgeons (ASBrS) and the Society of Breast Imaging (SBI) developed guidelines for…
Woman Presenting With Calvarial Mass
A 48-year-old woman presented with episodic headaches, light sensitivity, and a painful, pulsating mass on her forehead. What is your diagnosis?
