Dowling-Degos Disease
This case report describes reticulated hyperpigmented macules interspersed with scattered papules and comedone-like lesions within the axillary and inguinal folds that extended over the neck, scalp, and facial regions.
Medical Knowledge
Chronic Spontaneous Urticaria
This Clinical Insights outlines the clinical characteristics, diagnostic approach, and therapeutic strategies for managing chronic spontaneous urticaria.
Microplastics and Human Health
This JAMA Insights discusses rising detection of microplastics in human tissue and the importance of international cooperation to limit plastic pollution.
Multidisciplinary Treatment of Patients With Noonan Syndrome – A Consensus Statement
Importance Noonan syndrome (NS) is a rare developmental disorder and the most common condition among the RASopathies. Diagnosis and treatment of NS can be challenging due to the wide phenotypic variability of its manifestations. A multidisciplinary approach is essential, with continuous…
The Difficult Cholecystectomy
Importance Difficult cholecystectomies are associated with a higher risk of severe bilio-vascular injuries. Observations Obesity, cirrhosis, high American Society of Anesthesiologists score, previous abdominal operations, and presence of acute cholecystitis or common bile duct stones are associated with difficult cholecystectomies. On imaging,…
Midline Tongue Defect in a Pediatric Patient
A male infant presented with an anterior midline tongue indentation. What is your diagnosis?
Painful Hand Swelling With Finger Contractures
A 56-year-old woman with no history of rheumatic disease or hand injury had swelling and tenderness of the bilateral wrists, metacarpophalangeal and proximal interphalangeal joints, nodular palmar tendon thickening, and flexion contractures of all fingers; results of serologic testing for…
Exemestane-Associated Bilateral Maculopathy
This case report discusses a diagnosis of medication-associated maculopathy in a 44-year-old woman receiving exemestane treatment after breast cancer resection.
Posterior Lenticonus and Intralenticular Cracks on School Visual Screening
This case report discusses a diagnosis of posterior lenticonus with intralenticular cracks found during a school vision screening in a girl aged 8 years referred for decreased visual acuity in the left eye.
Iridolenticular Burns After Panretinal Photocoagulation
This case report describes anterior-segment burns of the nasal pupillary margin with adjacent anterior lenticular opacities in a patient receiving panretinal photocoagulation for proliferative diabetic retinopathy.
