A 34-year-old man with no significant medical history presented with progressive dysphonia, dysphagia, and an infiltrative laryngeal mass that remained nondiagnostic on multiple biopsies. What was the diagnosis?
Importance Patent protection allows pharmaceutical companies to charge high prices for prescription drugs during periods of market exclusivity, and their expiration usually defines when generic competitors can enter the US market. Patents on drug active ingredients are classified as primary…
Importance Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is a demyelinating disease distinct from multiple sclerosis (MS) and aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder (AQP4+NMOSD). Magnetic resonance imaging (MRI) is central to confirming attacks, defining lesion distribution, and excluding alternative diagnoses…
Importance Mental disorders are a leading cause of disability worldwide, and their burden continues to increase across Africa. Despite growing need, access to care remains limited, with treatment gaps reaching up to 90% in some settings. These gaps reflect longstanding…
Importance Low-dose oral minoxidil (LDOM) is increasingly used off-label to treat pediatric hair disorders; however, standardized guidance for patient selection, dosing, safety, and monitoring in patients younger than 12 years is lacking. Objective To establish expert consensus recommendations for LDOM…
This case report discusses a finding of ectopic hepatic tissue near the inferior vena cava orifice found on incidental examination of a 31-year-old pregnant woman.
A man with suspected but untreated secondary syphilis had nonscarring alopecia, photodistributed facial eruption, oral ulcers, leukopenia, and low C3 level; biopsy of a palmar lesion showed dyskeratotic keratinocytes, basal vacuolar alteration, papillary dermal edema, and perivascular and periappendageal infiltrates…
This article discusses research providing renewed reasons to revisit the utility of glutamatergic drugs for treating schizophrenia.
A man in his 30s presented with a 5-year history of generalized keratotic papules and plaques accompanied by pruritus. Physical examination revealed numerous dark-red keratotic papules on the trunk and extremities as well as seborrheic dermatitislike erythematous scaly patches on…
The curriculum includes over 48.25 hours of training and will lead to a certificate of completion from the UCI School of Medicine. • Two-weekend intensive training (28.25 CME hours) • One hour per month of mentoring sessions with a TNT…
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