Antibiotics for Pediatric Acute Bacterial Sinusitis
This JAMA Insights examines antibiotic selection for the treatment of acute bacterial rhinosinusitis in US pediatric patients, specifically amoxicillin vs amoxicillin-clavulanate.
ABMS Lifelong Learning CME Activity
Perianal Paget Disease
This case report describes a woman in her 70s with an erythematous plaque with superficial erosion, focal white scale, and surrounding hyperpigmentation located circumferentially around the anus and extending anteriorly to involve the perineum.
Toward Equitable Interventions in Public Mental Health – A Review
Importance The field of public mental health is evolving to tackle the profound impact of global challenges such as climate change, migration, and health crises. These issues accentuate health and social inequities, necessitating a focus on how to achieve interventions that…
Aortic Stenosis, Heart Failure, and Aortic Valve Replacement
Importance Heart failure (HF) and aortic stenosis (AS) frequently coexist, presenting a complex clinical challenge due to their intertwined pathophysiology and associated high morbidity and mortality. Despite numerous advancements in transcatheter and surgical aortic valve replacement (AVR), HF decompensation remains the…
Large Retinal Cystoid Abnormality on Ultra-Widefield Swept-Source OCT
This case report discusses a diagnosis of retinal cystoid abnormality and retinal detachment on ultra-widefield optical coherence tomography (OCT) in the setting of fluctuating visual loss in the right eye.
Central Retinal Artery Revascularization Promptly After Tenecteplase
This case report discusses a diagnosis of central retinal artery occlusion and visual prognosis after management with intravenous tenecteplase.
Acute Transient Cataract Associated With 5-Fluorouracil
This case report discusses a diagnosis of transient cataract in the setting of 5-fluorouracil injection to treat a fibrotic trabeculectomy bleb.
Buprenorphine/Naloxone vs Methadone for the Treatment of Opioid Use Disorder
Importance Previous studies on the comparative effectiveness between buprenorphine and methadone provided limited evidence on differences in treatment effects across key subgroups and were drawn from populations who use primarily heroin or prescription opioids, although fentanyl use is increasing across North…
Subconjunctival Mass 30 Years After Melanoma Resection
A 70-year-old male is referred for evaluation of a conjunctival mass in the right eye, which has grown slowly over 27 years. Examination reveals a superonasal, multilobulated, pigmented lesion with episcleral feeder vessels and spontaneous vascular pulsations within the intraocular…
Making the Ethical Oversight of All Clinical Trials Fit for Purpose
Importance With the increase in trials assessing comparative effectiveness of approved products and alternative care strategies, guidance is needed to ensure ethical oversight is fit for purpose for the risks, burdens, and constraints on choice this research presents. Observations US regulations governing…
