This case report highlights a temporal relationship between the use of a glucagon-like peptide-1 receptor (GLP-1) agonist and the occurrence of central retinal artery occlusion.
Importance Perforated peptic ulcer disease (PUD) affects 4 million people annually worldwide, with a lifetime prevalence of 5% to 10%. Of those affected, 5% will progress to the point of perforation. Despite advances in the understanding and treatment, perforated PUD continues…
Importance Suicide is a public health crisis, and despite renewed efforts to confront this problem, suicide rates continue to rise in the US. While suicide prevention encompasses a broad array of strategies, treatment development is lagging. Within this realm, clinical trials…
This case report describes a young, elementary school aged boy with nevus anemicus.
This JAMA Insights discusses selection of catheters for medium- or long-term use in 4 clinical settings.
Importance Disparities in eye health are associated with lower-income and minoritized populations, many of whom seek care at federally qualified health centers (FQHCs). Objective To examine the literature addressing vision and eye health care provided at FQHCs, identify barriers to providing care…
Importance Understanding health conditions with the most spending and variation across locations and over time is important for identifying trends, highlighting inequalities, and developing strategies for lowering health spending. Objective To estimate US health care spending for each of 3110 US counties,…
Importance Neurological examinations traditionally rely on visual analysis of physical clinical signs, such as tremor, ataxia, or nystagmus. Contemporary score-based assessments aim to standardize and quantify these observations, but these tools suffer from clinimetric limitations and often fail to capture subtle…
Importance Nearly 5% of adults have the precursor malignant condition monoclonal gammopathy of unknown significance (MGUS). Management centers on differentiating MGUS from more serious conditions to determine additional diagnostic testing, monitoring, and potential therapy. Observations MGUS is defined by the absence of…
This Guide to Statistics and Methods provides an overview of platform trials, describes the characteristics that make them more efficient for evidence generation, and discusses their limitations.
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