Importance Immune thrombotic thrombocytopenic purpura (iTTP) is a life-threatening thrombotic microangiopathy that presents with microangiopathic hemolytic anemia (MAHA) and thrombocytopenia. Worldwide annual incidence of iTTP is 2 cases per million to 6 cases per million. Observations Immune TTP is caused by an…
A man in his 30s presented with a 6-month history of asymptomatic yellow-brown plaques on the first digits of his feet that were unresponsive to urea cream and clobetasol treatment. What is your diagnosis?
This JAMA Insights discusses the FDA approval of remestemcel-L-rknd to treat graft-vs-host disease in children and provides regulatory considerations for this approval.
This case report describes an echocardiography-based diagnosis of left ventricular noncompaction cardiomyopathy in a male patient in his 40s who presented with sudden-onset dyspnea.
A 20-year-old Chinese male competitive swimmer presented with bilateral conductive hearing loss; single-stage surgery was performed to remove a cholesteatoma. Postoperative computed tomography scans revealed an unusual finding. What is your diagnosis?
A woman in her 50s with a history of hemochromatosis, psoriasis, and type 2 diabetes presented with a 3-month history of abdominal pain, weight loss, and a large palpable fixed abdominal mass. What is your diagnosis?
Importance Survivors of thyroid cancer represent 10% of all cancer survivors in the US, yet their unmet care needs remain unexplored. Understanding the unmet care needs of survivors of thyroid cancer could help develop targeted interventions to enhance their quality of…
This case report describes an 8-year-old girl who presented with cerebrospinal fluid rhinorrhea, brain sagging, and orthostatic headaches.
This Clinical Insights discusses factors clinicians should consider when prescribing denosumab among postmenopausal women with osteoporosis.
Dr Jessi Gold, inaugural chief wellness officer for the University of Tennessee (UT) System, associate professor of psychiatry at the University of Tennessee Health Science Center (UTHSC), practicing outpatient psychiatrist, and author of the book, How Do You Feel?: One…
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