Foscarnet-Induced Penile Ulceration
This case report describes an uncircumcised male individual with tender perimeatal erythema and ulceration extending to the right glans.
ABMS Lifelong Learning CME Activity
Multiple Long-Standing Papules and Nodules on the Left Lower Leg
A woman in her 60s with long-standing thickening and induration of the legs presented with 1 week of left leg pain. Physical examination results revealed multiple firm skin-colored papules and nodules coalescing to form a large plaque on the anterior…
Erroneous Rapid Exchange Balloon Inflation During Coronary Angioplasty in a Male Patient in His 70s With Chronic Stable Angina
This case report discusses an erroneous rapid exchange balloon inflation during coronary angioplasty in a patient who presented with a right coronary artery lesion on angiography.
Sedentary Behavior and Incident Dementia Among Older Adults
Importance Sedentary behavior is associated with cardiometabolic disease and mortality, but its association with dementia is unclear. Objective To investigate whether accelerometer-assessed sedentary behavior is associated with incident dementia. Design, Setting, and Participants A retrospective study of prospectively collected data from the UK…
Aspirin for Secondary Prevention of Cardiovascular Disease in 51 Low-, Middle-, and High-Income Countries
Importance Aspirin is an effective and low-cost option for reducing atherosclerotic cardiovascular disease (CVD) events and improving mortality rates among individuals with established CVD. To guide efforts to mitigate the global CVD burden, there is a need to understand current levels…
Preexposure Prophylaxis for the Prevention of HIV – Updated Evidence Report and Systematic Review for the US Preventive Services Task Force
Importance A 2019 review for the US Preventive Services Task Force (USPSTF) found oral preexposure prophylaxis (PrEP) associated with decreased HIV infection risk vs placebo or no PrEP in adults at increased HIV acquisition risk. Newer PrEP regimens are available. Objective To…
Preexposure Prophylaxis to Prevent Acquisition of HIV – US Preventive Services Task Force Recommendation Statement
Importance An estimated 1.2 million persons in the US currently have HIV, and more than 760 000 persons have died of complications related to HIV since the first cases were reported in 1981. Although treatable, HIV is not curable and has significant…
Prenatal Intravenous Magnesium at 30-34 Weeks’ Gestation and Neurodevelopmental Outcomes in Offspring – The MAGENTA Randomized Clinical Trial
Importance Intravenous magnesium sulfate administered to pregnant individuals before birth at less than 30 weeks’ gestation reduces the risk of death and cerebral palsy in their children. The effects at later gestational ages are unclear. Objective To determine whether administration of magnesium…
Coin-Shaped Opacities in the Stomach
On day 7 after hospital admission, a patient with end-stage kidney disease prescribed sevelamer, hydrocodone-acetaminophen, hydromorphone, and chewable lanthanum tablets developed intermittent apneic episodes, bilateral rhonchi, and responsiveness to verbal commands only with deep painful stimulus; a chest radiograph showed…
Screening for Depression and Suicide Risk in Adults – US Preventive Services Task Force Recommendation Statement
Importance Major depressive disorder (MDD), a common mental disorder in the US, may have substantial impact on the lives of affected individuals. If left untreated, MDD can interfere with daily functioning and can also be associated with an increased risk of…
