This case report describes a diagnosis of iris metastasis in a 78-year-old woman with small cell lung cancer who presented with blurred vision and redness in the right eye accompanied by headache and nausea.
Importance The Ending the HIV Epidemic (EHE) initiative aims to reduce new HIV infections in the US by 75% in 2025 and 90% in 2030, prioritizing 57 US jurisdictions with the highest incidence rates. Although Latino gay, bisexual, and other men…
Importance The prevalence of metabolic dysfunction–associated steatotic liver disease (MASLD) in the US is highest among Hispanic/Latino individuals. Their risk of developing metabolic dysfunction–associated steatohepatitis (MASH) with fibrosis, cirrhosis with progression to hepatocellular carcinoma and need for liver transplant, and death…
This case report describes a man who self-diagnosed rapid-eye-movement (REM) sleep behavior disorder using a sleep-tracking wearable device, later confirmed by a sleep evaluation.
This JAMA Insights provides evidence-based recommendations for communicating numerical information to patients.
A previously healthy 55-year-old man presented to his local family medicine clinic after waking up with a buzzing sensation in his chest. What would you do next?
A woman in her 30s presented with a 1-year history of painful annular eruptions on the anterior neck, which initially appeared as several erythematous papules that gradually enlarged, coalescing into annular configurations that were occasionally accompanied by pain. What is…
Importance Head and neck squamous cell carcinoma (HNSCC) represents a significant global health burden with limited therapeutic options for patients with recurrent or metastatic disease. Epidermal growth factor receptor (EGFR) is overexpressed in most patients with HNSCC and represents a biologically…
Importance Rising rates of early-onset cancer have generated substantial media coverage and public concern. In response, early-onset cancer has become a federal research priority, and clinical guidelines have shifted to recommend earlier screening for some cancers. Yet, it remains unclear whether…
Importance Suicide is a leading cause of death among young people and an escalating public health crisis. Objective To assess the effectiveness and harms of available treatments for suicidal thoughts and behaviors among youths at heightened risk for suicide. Evidence Review A systematic…
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