ABMS Lifelong Learning CME Activity

Recommendations to Improve Quality of Probiotic Systematic Reviews With Meta-Analyses

Importance  Systematic reviews and meta-analyses often report conflicting results when assessing evidence for probiotic efficacy, partially because of the lack of understanding of the unique features of probiotic trials. As a consequence, clinical decisions on the use of probiotics have been…

Cannabis Exposure and Adverse Pregnancy Outcomes Related to Placental Function

Importance  Cannabis use is increasing among reproductive-age individuals and the risks associated with cannabis exposure during pregnancy remain uncertain. Objective  To evaluate the association between maternal cannabis use and adverse pregnancy outcomes known to be related to placental function. Design, Setting, and…

Cheating the Rules of Admission With “Observation”

When physicians admit patients to a hospital, their decisions about where—and to whose professional stewardship and services—those patients belong are influenced by federal policies, of which many clinicians are not aware. The distinction between observation and admission has clinical and…

Neonatal Survival After Serial Amnioinfusions for Bilateral Renal Agenesis – The Renal Anhydramnios Fetal Therapy Trial

Importance  Early anhydramnios during pregnancy, resulting from fetal bilateral renal agenesis, causes lethal pulmonary hypoplasia in neonates. Restoring amniotic fluid via serial amnioinfusions may promote lung development, enabling survival. Objective  To assess neonatal outcomes of serial amnioinfusions initiated before 26 weeks’ gestation…

Reporting of Factorial Randomized Trials – Extension of the CONSORT 2010 Statement

Importance  Transparent reporting of randomized trials is essential to facilitate critical appraisal and interpretation of results. Factorial trials, in which 2 or more interventions are assessed in the same set of participants, have unique methodological considerations. However, reporting of factorial trials…

Syndromic Pattern Recognition in Infection Prevention and Control

Ensuring the health and safety of health care professionals and patients from transmissible diseases is paramount to a robust health care system. Quick identification of potential infections and the implementation of effective infection prevention and control measures are key to…