Journal-based

A 51-Year-Old Woman With Abnormal Corpus Callosum Signal

A 51-year-old woman presented with a 2-year history of progressive memory loss and left limb numbness. Imaging showed multifocal restricted diffusion in the corpus callosum and diffuse subcortical white matter hyperintensities and corpus callosum atrophy. What is your diagnosis?

Strategies to Improve Medical Communication

This JAMA Insights summarizes strategies for effective medical communication, with considerations for the message delivered, the messenger source, and the social context.

Anterior Chamber Snowflake After Keratoplasty

A 62-year-old woman presented with painless vision reduction and eye redness in the right eye for a week. Nine months after keratoplasty, she presented with diffuse tiny nodules all over the iris and a dense opacity in the anterior vitreous…

Sudden ST-Segment Changes in a Critically Ill Patient

A patient in his mid-60s underwent bilateral orthotopic lung transplant and is later hospitalized for sepsis from pneumonia complicated by acute transplant rejection, without any cardiac symptoms. He develops severe acute respiratory distress syndrome requiring intubation and paralysis. Electrocardiography shows…

A Painless Right Anterior Neck Mass

A 58-year-old woman presents with a several-week history of a painless right-sided swelling on her anterior neck. What is your diagnosis?

A 52-Year-Old With Painful Fingertips

A patient had cold, cyanotic fingertips with small ulcerations. Laboratory testing showed leukocytosis, eosinophilia, and elevated D-dimer level; results of tests for antinuclear antibodies, antiphospholipid antibodies, antineutrophil cytoplasmic antibodies against proteinase 3 and myeloperoxidase, and HIV were negative. What is…