Sudden Hemodynamic Deterioration of a 75-Year-Old Woman With Progressive Jaw Pain
This case report describes a diagnosis of left ventricular anterior free-wall rupture in a patient given anticoagulant treatment for subacute myocardial infarction.
Journal-based
Climate Change and Preventable Injuries
This JAMA Insights investigates the increased rates of climate change’s related preventable injury and the importance of emergency and disaster preparedness as well as injury and violence prevention.
Bringing Imaging Biomarkers Into Clinical Reality in Psychiatry
Importance Advancing precision psychiatry, where treatments are based on an individual’s biology rather than solely their clinical presentation, requires attention to several key attributes for any candidate biomarker. These include test-retest reliability, sensitivity to relevant neurophysiology, cost-effectiveness, and scalability. Unfortunately, these…
Diagnosis, Risk Stratification, and Treatment of Pericarditis – A Review
Importance Pericarditis accounts for up to 5% of emergency department visits for nonischemic chest pain in North America and Western Europe. With appropriate treatment, 70% to 85% of these patients have a benign course. In acute pericarditis, the development of constrictive…
A Conjunctival Papillary Tumor in a 77-Year-Old Woman
A 77-year-old woman presents to the ophthalmology department with a 5-year history of a painless neoplasm in her left eye and no history of tumors. Slitlamp examination shows a papillary tumor on the limbal conjunctiva, with blood vessels extending to…
Balloon Angioplasty vs Medical Management for Intracranial Artery Stenosis – The BASIS Randomized Clinical Trial
Importance Previous randomized clinical trials did not demonstrate the superiority of endovascular stenting over aggressive medical management for patients with symptomatic intracranial atherosclerotic stenosis (sICAS). However, balloon angioplasty has not been investigated in a randomized clinical trial. Objective To determine whether balloon…
Scabies, Bedbug, and Body Lice Infestations – A Review
Importance Scabies, bedbug, and body lice infestations are caused by organisms that live on or in the skin, on clothing, or in the environment and commonly cause pruritus and rash. In 2021, approximately 622 million incident cases of scabies occurred globally….
Telehealth vs In-Person Early Palliative Care for Patients With Advanced Lung Cancer – A Multisite Randomized Clinical Trial
Importance Numerous studies show that early palliative care improves quality of life and other key outcomes in patients with advanced cancer and their caregivers, although most lack access to this evidence-based model of care. Objective To evaluate whether delivering early palliative care…
Prioritization of Psychopathological Symptoms and Clinical Characterization in Psychiatric Diagnoses – A Narrative Review
Importance Psychiatry mainly deals with conditions that are mediated by brain function but are not directly attributable to specific brain abnormalities. Given the lack of concrete biological markers, such as laboratory tests or imaging results, the development of diagnostic systems is…
Necrotizing Soft Tissue Infections – A Review
Importance Necrotizing soft tissue infections (NSTIs) are severe life- and limb-threatening infections with high rates of morbidity and mortality. Unfortunately, there has been minimal improvement in outcomes over time. Observations NSTIs are characterized by their heterogeneity in microbiology, risk factors, and anatomical…
