A man aged 61 years presented with chronic progressive weakness and gait dysfunction over a 4-year period. He had Ashkenazi Jewish ancestry and a history of memory loss, inappropriate laughter, dysarthria, and hypertension. Examination revealed impaired recall, extremity spasticity, distal…
This JAMA Insights explores how considering clinical factors and/or potential exposures during the premigration, migration, and postmigration phases of immigration could help clinicians more effectively treat patients born outside the US.
A 41-year-old immunocompromised man presented to the intensive care unit with neutropenic fevers, and after a 1-week stay, developed oral ulcers and tender, diffuse, erythematous pseudovesicular papules, many umbilicated, on the face, trunk, and extremities. What is your diagnosis?
This case report describes a diagnosis of xanthelasma in a man in his 40s who adopted a carnivore diet 8 months before presentation.
Importance Airway stenosis is a rare but debilitating disorder that significantly degrades the quality of life in affected patients. Treatments are primarily surgical, and disease management lacks established medical therapies. The North American Airway Collaborative held its third symposium at The…
Importance Patients undergoing unplanned abdominal surgical procedures are at increased risk of surgical site infection (SSI). It is not known if incisional negative pressure wound therapy (iNPWT) can reduce SSI rates in this setting. Objective To evaluate the effectiveness of iNPWT in…
Importance Essential thrombocythemia, a clonal myeloproliferative neoplasm with excessive platelet production, is associated with an increased risk of thrombosis and bleeding. The annual incidence rate of essential thrombocythemia in the US is 1.5/100 000 persons. Observations Patients with essential thrombocythemia have a persistent…
Importance Care management benefits community-dwelling patients with dementia, but studies include few patients with moderate to severe dementia or from racial and ethnic minority populations, lack palliative care, and seldom reduce health care utilization. Objective To determine whether integrated dementia palliative care…
Importance Surgery is frequently required for hidradenitis suppurativa (HS) treatment, but the impact of common comorbidities such as obesity, diabetes, and smoking on outcomes has been sparsely studied. Observations A total of 12 studies met final inclusion criteria for investigating complication rates…
A 58-year-old woman with no allergies or rheumatic disease had a 2-year history of spontaneous wheals that occurred daily, accompanied by pruritus, arthralgia, and intermittent fevers; the wheals resolved after several hours without residual hyperpigmentation or bruising. C-reactive protein level…
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