Journal-based

Why Does the History of Circadian Rhythms Matter for Sleep Today?

A paradigm shift in circadian science is underway, exposing ethical tensions from a legacy of pervasive neglect of circadian disorders. This article canvasses ethical questions about stigma, justice, and accommodation that should be formally recognized to reconceive circadian care. Responding…

When Should Pharmacological Interventions for Insomnia Be Recommended?

This commentary on a case describes how social determinants of health also contribute to insomnia and then suggests how to balance risks and benefits of different strategies for managing chronic insomnia. Behaviorally induced insufficient sleep syndrome can exacerbate morning side…

We’re All Healthier Under a Starry Sky

A star-filled sky has long been a source of awe and inspiration, and its loss adversely affects human, nonhuman, and environmental health. In one generation, this majestic nighttime overstory has been lost due to national and international overuse of light-emitting…

How Should Clinicians Partner With Families to Promote Children’s Sleep Health?

Short sleep duration, poor sleep quality, and irregular timing of sleep are prevalent sleep troubles for children, but fully assessing children’s sleep environments and effectively promoting children’s overall sleep health is nearly impossible during brief clinical encounters. This commentary on…

Dialysis for Chronic Kidney Failure – A Review

Importance  More than 3.5 million people worldwide and 540 000 individuals in the US receive maintenance hemodialysis or peritoneal dialysis for the treatment of chronic kidney failure. The 5-year survival rate is approximately 40% after initiation of maintenance dialysis. Observations  Hemodialysis and peritoneal…

Primary Cutaneous Nocardiosis

This case report describes a woman in her 20s with lesions on the right ring finger that evolved into pustules.

Biomarkers to Inform Prognosis and Treatment for Unresectable or Metastatic GEP-NENs

Importance  Evidence-based treatment decisions for advanced gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) require individualized patient-centered decision-making that accounts for patient and cancer characteristics. Objective  To create an accessible guidance document to educate clinicians and patients on biomarkers informing prognosis and treatment in unresectable or…

Periocular Swelling, Fever, and Organomegaly in a 4-Year-Old Child

A child aged 4 years presented with a 3-day history of worsening redness, pain, and swelling over the left lower eyelid and nose. Visual acuity was normal, and systemic examination revealed cervical lymphadenopathy and hepatosplenomegaly. The patient showed no improvement…

Supervised Exercise Therapy for Peripheral Artery Disease

This Teachable Moment discusses a woman in her 60s with hypertension, hyperlipidemia, coronary artery disease, and smoking history who presented with bilateral, aching leg pain triggered by walking and relieved by rest.

Over-the-Counter Oral Contraceptives

This JAMA Insights in the Women’s Health series discusses the first over-the-counter progestin-only oral contraceptive available in the US, including its effectiveness, mechanism of action, and accessibility.