Patient-Centered Buprenorphine Dosing in the Fentanyl Era
This Teachable Moment discusses initiation, optimization, and long-term use of buprenorphine in man with an opioid use disorder.
Journal-based
Chronic Neuropsychiatric Sequelae Associated With Kambo Intoxication
This case report describes a 35-year-old female patient experiencing chronic neuropsychiatric symptoms related to kambo, a secretion of the South American giant leaf frog, and noted abnormalities on initial magnetic resonance imaging with subsequent resolution.
Cardiac CT Calcium Score
This JAMA Insights explores how coronary artery calcium and computed tomography calcium scores can improve risk assessment for atherosclerotic cardiovascular disease and inform recommendations for statin therapy.
Alopecia Areata–Specific Patient-Reported Outcome Measures
Importance Alopecia areata (AA) has a high prevalence worldwide and causes considerable morbidity in patients. Patient-reported outcomes (PROs) have become an important component of clinical outcome assessment. The quality of existing AA-specific PRO measures (PROMs) has not been evaluated to date….
Circular Necrotic Yellow-Red Plaque on the Chest
A man in his 40s presents with a progressively enlarging yellow-red plaque on the chest with multiple central yellow papules, open comedones, and telangiectasia. What is your diagnosis?
Subungual Amelanotic Melanoma
This case report describes a light pink plaque underneath an atrophied and broken nail plate that was surrounded by depigmentation.
Coronary Artery Calcium Testing—Too Early, Too Late, Too Often
Importance Traditional risk factors, enhancing factors, and risk scores help clinicians assess atherosclerotic cardiovascular disease (ASCVD) risk for primary prevention. The latest cholesterol guidelines suggest measuring coronary artery calcium (CAC) score by computed tomography (CT) in those at intermediate risk when…
Conjunctival Nodule in a Female With Ulcerative Colitis
A 69-year-old woman developed a nodule in her left eye and reported bilateral eye fatigue, burning, and irritation. The patient had ulcerative colitis, type 2 diabetes, gastroesophageal reflux disease, hypertension, and glaucoma in her right eye. What is your diagnosis?
Eating Disorders – A Review
Importance Eating disorders are characterized by disturbances in eating behavior and occur worldwide, with a lifetime prevalence of 2% to 5%. They are more common among females than males and may be associated with medical and psychiatric complications, impaired functioning, and…
Current Progress and Future Directions of Immunotherapy in Head and Neck Squamous Cell Carcinoma – A Narrative Review
Importance For decades, the 3 therapeutic pillars for head and neck squamous cell carcinoma (HNSCC) have been radiation therapy, chemotherapy, and surgery. In recent years, a fourth pillar, immunotherapy, has shifted the existing paradigm of oncologic care by improving survival outcomes….
