Importance The fallopian tube epithelium has been demonstrated to be an important source of tubo-ovarian carcinoma. Therefore, removal of the fallopian tubes during unrelated pelvic or abdominal surgery (opportunistic salpingectomy) can potentially lower future ovarian cancer risk. Objectives To assess current evidence…
This case report describes a patient in her early 60s who presented with substernal chest pain and diaphoresis.
This Clinical Insights outlines the clinical characteristics, diagnostic approach, and therapeutic strategies for managing scarring alopecias.
Despite legislative attention from Congress in the 1980s, diagnostic research on rare diseases is not lucrative enough to garner sufficient private funding. The Undiagnosed Diseases Network supports diagnostic research and intervention innovation for patients with undiagnosed or rare conditions. This…
For persons living with an undiagnosed disease and their families, finding an accurate diagnosis can be a long and complex process. Having a rare condition that goes undiagnosed for a long period constitutes a significant part of these patients’ disease…
Patient-subjects’ participation in an Undiagnosed Diseases Network (UDN) protocol can afford access to innovative diagnostic techniques, especially in genomic medicine, which can shorten the time it takes to accurately diagnose a so-called “medical mystery.” But UDN research processes can be…
This JAMA Insights explores the management of severe refractory asthma, including medications, access to specialists, and managing environmental triggers.
The Undiagnosed Diseases Network is a national consortium of clinicians and researchers working to promote diagnostic research and accurately diagnose patients with rare diseases, many of whose conditions have long gone undiagnosed. This endeavor’s importance should not, however, stop us…
Patients with undiagnosed conditions often experience frustration and lose trust in health care. This article suggests how faculty in academic health centers can prepare their students and trainees to respond with care to the vulnerabilities and needs of patients seeking…
Importance Bariatric surgery is widely recognized for its health benefits; however, its association with work productivity and employment participation, though frequently reported, has not been systematically synthesized. This evidence is crucial to inform the economic evaluation of bariatric surgery. Objective To systematically…
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