Journal-based

Extensive Oral Ulcerations After Stem Cell Transplant

A 69-year-old male patient presented with worsening new-onset oral ulcerations and pain. He had myelodysplastic syndrome and underwent an allogeneic hematopoietic stem cell transplant 18 months prior. What is your diagnosis?

Rapidly Enlarging Facial Mass Following SARS-CoV-2 Infection

A female adolescent presented with a 1-month history of a rapidly enlarging, vegetative mass on her right cheek after a symptomatic SARS-CoV-2 infection with high fever. What is your diagnosis?

Mental Disorders as Homeostatic Property Clusters – A Narrative Review

Importance  Psychiatric classification faces longstanding challenges, including heterogeneous diagnostic categories, high comorbidity rates, limited interrater reliability, and modest clinical utility. Successive revisions of systems such as the DSM since 1980 have done little to resolve these issues. How to move forward? Observations  This narrative…

Peanut Allergy

This JAMA Insights discusses peanut allergy, including diagnosis, introduction of peanuts to infant diet, and immunotherapy options.

Solitary Verrucous Plaque on the Right Pretibial Region

A man in his 50s presented with a 4-month history of pruritic, verrucous lesions on the right lower leg. Physical examination revealed a well-demarcated, verrucous plaque on the right pretibial region, with elevated borders, superficial pustules, exudates, peripheral erythema, and…

Obesity and Cancer – A Translational Science Review

Importance  Obesity is associated with increased risk of cancer, including endometrial, esophageal, gastric, kidney, colorectal, liver, gallbladder, pancreas, prostate, postmenopausal breast, ovarian, and thyroid cancers. Overweight and obesity account for approximately 10% of new cancer diagnoses annually in the US and…

Cannabis and Mental Health – A Review

Importance  Cannabis use is common among those with mental health conditions, and many people report using cannabis to manage mental health symptoms. It is important for clinicians to understand the lack of clear benefits of cannabis for mental health conditions and…

Defining Surgical Shared Decision-Making for Older Adults Using the RAND/UCLA Appropriateness Method – A Consensus Statement

Importance  Older adults undergoing major surgery often face increased risks of functional decline, cognitive impairment, and loss of independence. While shared decision-making (SDM) is recommended, there are no standardized guidelines defining its key components for this population. Objective  To identify valid and…