JAMA Dermatology

Solitary Verrucous Plaque on the Right Pretibial Region

A man in his 50s presented with a 4-month history of pruritic, verrucous lesions on the right lower leg. Physical examination revealed a well-demarcated, verrucous plaque on the right pretibial region, with elevated borders, superficial pustules, exudates, peripheral erythema, and…

Purpuric Edematous Papules in a Man With Prostate Cancer

A man in his 60s undergoing radiotherapy for prostate cancer presented to the dermatology clinic with a 1-week history of a tender, pruritic rash to the trunk and extremities. What is your diagnosis?

Subcorneal Pustular Dermatosis

This case report describes a pruritic rash on the trunk and erythematous patches with numerous flaccid, half-half pustules that contained clear and purulent fluid.

Diffuse Alopecia of the Scalp and Eyebrows

A man in his 30s presented with a 2-month history of hair loss on the entire scalp and the lateral portions of both eyebrows. Results of the hair-pull test were negative. What is your diagnosis?

Multicentric Reticulohistiocytosis

This case report describes large areas of erythema on the face, chest, and back with relatively clear boundaries and swollen hands with scattered skin-colored papules and nodules.

Genotype-Phenotype Correlations in Recessive Dystrophic Epidermolysis Bullosa – A Systematic Review

Importance  Recessive dystrophic epidermolysis bullosa (RDEB) is a rare monogenic blistering disorder with wide clinical heterogeneity, ranging from localized skin fragility to life-limiting systemic complications. Understanding genotype-phenotype correlations in COL7A1, the causative gene, is critical for clinical prognostication, genetic counseling, and the…

Approach to Scarring Alopecia

This Clinical Insights outlines the clinical characteristics, diagnostic approach, and therapeutic strategies for managing scarring alopecias.

Patient Values and Preferences in Chronic Urticaria Treatment – A Systematic Review

Importance  Patient and caregiver values and preferences should inform clinical management. An update to the American Academy of Allergy, Asthma & Immunology/American College of Allergy, Asthma and Immunology’s Joint Task Force on Practice Parameters guidelines on chronic urticaria (CU) plans to…