JAMA Dermatology

HutchinsonñGilford Progeria Syndrome

This case report describes a boy younger than 2 years with Hutchinson-Gilford progeria syndrome.

Asymptomatic Yellow-Brown Plaques on the Great Toes

A man in his 30s presented with a 6-month history of asymptomatic yellow-brown plaques on the first digits of his feet that were unresponsive to urea cream and clobetasol treatment. What is your diagnosis?

Alkaptonuria

This case report describes a man in his 50s with progressive blue-gray discoloration of sun-exposed areas, including the nose, cheeks, ears, and hands.

Papular and Vesicular Lesions on the Vulva and Thighs

A woman in her 60s, who had undergone hysterectomy, adnexectomy, and concurrent chemoradiotherapy for cervical cancer 8 years prior, presented with a 2-year history of painful pink vesicular and papular lesions on the vulva and thighs. What is your diagnosis?

Asymptomatic Symmetrical Telangiectasia on Lower Extremities

A man in his 60s with a history of hypertension, hyperlipidemia, and coronary artery disease presented with symmetrical diffuse, reticulated telangiectatic macules covering the legs and forearms. Dermoscopy revealed prominent fine telangiectasias, which was blanchable on pressure. What is your…

Defining On-Treatment Remission in Plaque Psoriasis – A Consensus Statement From the National Psoriasis Foundation

Importance  Defining on-treatment remission in plaque psoriasis is important for benchmarking patient responses to therapies. This also helps to facilitate shared understanding, align treatment expectations, and enable more effective psoriasis management. Objective  To establish a consensus-based definition of on-treatment remission for plaque…