Medical Knowledge

Common Oral Conditions – A Review

Importance  Dry mouth, oral candidiasis, and recurrent aphthous ulcers are 3 of the most common oral conditions that may be associated with patient discomfort, decreased quality of life, and morbidity. Observations  In a meta-analysis of 26 population-based cohort and cross-sectional studies, the…

Human Whole-Eye Donation for Research Optimizing Clinical Trial Informed Consent

Importance  Posthumous whole-eye (globe) donations for research lack a mechanism that reinvolves the existing ophthalmic research team of the donor unless there is a preplanned donor directive. Disconnection between the deceased and their research team equates to lost opportunities for the…

Clinical, Biomarker, and Research Tests Among US Government Personnel and Their Family Members Involved in Anomalous Health Incidents

Importance  Since 2015, US government and related personnel have reported dizziness, pain, visual problems, and cognitive dysfunction after experiencing intrusive sounds and head pressure. The US government has labeled these anomalous health incidents (AHIs). Objective  To assess whether participants with AHIs differ significantly from…

Skin Biopsy Detection of Phosphorylated a-Synuclein in Patients With Synucleinopathies

Importance  Finding a reliable diagnostic biomarker for the disorders collectively known as synucleinopathies (Parkinson disease [PD], dementia with Lewy bodies [DLB], multiple system atrophy [MSA], and pure autonomic failure [PAF]) is an urgent unmet need. Immunohistochemical detection of cutaneous phosphorylated α-synuclein…

Entrustable Professional Activities in Surgery – A Review

Importance  Entrustable professional activities (EPAs) compose a competency-based education (CBE) assessment framework that has been increasingly adopted across medical specialties as a workplace-based assessment tool. EPAs focus on directly observed behaviors to determine the level of entrustment a trainee has for…

Give Them a Hand – Improving Hand Hygiene to Reduce HAIs

In this episode of Stories of Care, our host Megan Srinivas, MD, MPH talks with Michelle Doll, MD, a health system epidemiologist with Virginia Commonwealth University Health System, about the importance of hand hygiene in health care settings. Dr Doll…

Leveraging Segmented Harm Event Data to Drive Equity Improvement

This module is an overview of the third focus area of the equity-informed high-reliability learning series focused on advancing equity through five quality and safety focus areas. The main goals are to center historically marginalized voices by leveraging segmented harm…