Importance Hepatobiliary cancers are heterogeneous and molecularly complex. Recent advances in next-generation sequencing (NGS) have enhanced the understanding of their molecular landscape and enabled deployment of biomarker-based gene- and immune-targeted therapies. This review examines the role of molecular testing and targeted…
This JAMA Insights discusses recommendations for reducing the effects of surgical care on carbon emissions, including pre-, intra-, and postoperative changes to routine practices.
A 70-year-old man with a history of hypertension and chronic migraine presented with 10 months of progressive generalized muscle weakness and stiffness. Physical examination revealed generalized muscle wasting except for hypertrophy of bilateral shoulder muscles, and a deltoid muscle biopsy…
This case report discusses a diagnosis of intraventricular silicone oil discovered 2 years after silicone oil tamponade was performed for retinal detachment repair for proliferative diabetic retinopathy in a woman aged 54 years.
This case report discusses the depigmentation of retinal pigment epithelium (RPE) hypertrophy in a patient with Vogt-Koyanagi-Harada syndrome receiving high-dose corticosteroid treatment.
This case report discusses a diagnosis of Coats disease in a boy aged 15 months who was born at 37 weeksí gestation after an uncomplicated delivery.
Importance The most recent US clinical practice guideline (CPG) for tinnitus was published in 2014. The US Department of Veterans Affairs (VA)/US Department of Defense Tinnitus Clinical Practice Guideline Work Group recently completed a new guideline. The work group consisted of…
This JAMA Insights explores the use of different types of peripheral nerve blocks as an opioid-sparing pain strategy in the treatment of adults with hip fractures.
This case report describes a diagnosis of muscle infiltration of mycosis fungoides in a female aged 36 years with initial disease manifesting as pigmented skin patches.
Importance Autosomal dominant polycystic kidney disease (ADPKD) is characterized by progressive development of kidney cysts and is the most common inherited kidney disorder worldwide. ADPKD accounts for 5% to 10% of kidney failure in the US and Europe, and its prevalence…
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