Allogeneic Stem Cell Donation
This JAMA Insights discusses allogenic stem cell donation, including the donation process and the effects of stem cell donation on donors.
Medical Knowledge
Progressive Eyelid Lesions in a Woman With Essential Thrombocythemia
A 75-year-old woman with a history of essential thrombocythemia presented with 3 months of progressively enlarging right upper eyelid lesions. Examination revealed a thickened eyelid margin, madarosis, and erythema with some tenderness to palpation but an otherwise normal ocular examination….
Second Primary Cancer After Chimeric Antigen Receptor–T-Cell Therapy – A Review
Importance The commercialization of chimeric antigen receptor–T-cell (CAR-T) therapy has changed the landscape of treatment of hematological cancers. Numerous studies from the early 2000s paved the way for cell-based targeted therapeutics, which have been established as practice-changing therapies in lymphoma, leukemia,…
Early Screening for Latent Autoimmune Diabetes in Adults to Improve Care—Beyond the Routine
This Teachable Moment describes a man in his 30s who presented with a right diabetic foot ulcer and hyperglycemia and was assumed to have type 2 diabetes and was subsequently diagnosed with latent autoimmune diabetes in adults.
Spinal Cerebrospinal Fluid Leak Mimicking a Cerebellopontine Angle Tumor
This case report describes a patient ís experience after seeking a second opinion regarding a brain tumor.
Atrial Fibrillation – A Review
Importance In the US, approximately 10.55 million adults have atrial fibrillation (AF). AF is associated with significantly increased risk of stroke, heart failure, myocardial infarction, dementia, chronic kidney disease, and mortality. Observations Symptoms of AF include palpitations, dyspnea, chest pain, presyncope, exertional…
Which Values Should Guide Evidence-Based Practice?
This article draws on opinions in the AMA Code of Medical Ethics and applies them to evidence-based practice.
What Should Health Professions Students Learn About Data Bias?
In epidemiology, bias is defined as systematic deviation from the truth, and it can arise at different stages of scientific investigation (eg, data collection, methodological application, and outcomes analysis). Epidemiological bias can appear as a consequence of data bias (usually…
How Should Epidemiologists Respond to Data Genocide?
Data quality for and about American Indian/Alaska Native (AI/AN) people is undermined by deeply entrenched, colonial practices that have become standard in US federal data systems. This article draws on cases of maternal mortality and COVID-19 to demonstrate the ethical…
All About Cannabis Pharmacology
Pain expert Samer Narouze, MD, PhD talks about the pharmacology of cannabis, including the chemical structures, mechanism of action in the body, and pharmacodynamics of cannabinoids. This episode also addresses clinical information related to potential drug-drug interactions and adverse events…
