Medical Knowledge

A Large Sinonasal Mass in a Male Patient

A 59-year-old patient experienced months of progressively worsening left nasal obstruction. Physical examination revealed a papillomatous-appearing mass completely occupying the left nasal cavity. What is your diagnosis?

Skin Discoloration After Iatrogenic Fluorescein Dosing Error

This case report describes a diagnosis of iatrogenic fluorescein dosing error in a girl aged 10 months who presented for routine fluorescein angiography examination in the setting of incontinentia pigmenti.

Retinopathy After Epiretinal Membrane Peeling

This case report describes a diagnosis of maculopathy associated with mechanical trauma from epiretinal membrane peeling in a man aged 84 years.

Looking Beyond and Behind a Retinal Detachment

A 63-year-old woman with a history of type 1 diabetes presents with gradually progressive vision loss in the right eye for the past year. What would you do next?

Differential Legal Protections for Biologics vs Small-Molecule Drugs in the US

Importance  Biologics approved by the US Food and Drug Administration (FDA) receive 12 years of guaranteed protection from biosimilar competition compared with 5 years of protection from generic competition for new small-molecule drugs. Under the 2022 Inflation Reduction Act, biologics are…

About Whom Are We Talking When We Use Intellectual and Developmental Disabilities?

Importance  Communicating clearly about who is included in a population group is a critical element to effective dissemination and knowledge transfer. This narrative review highlights the inconsistency as it relates to communicating about individuals with intellectual disability (ID) and developmental disability…

Vertebral Web and Embolic Stroke

This case report describes a female individual in her 30s with headache and vertigo; examination revealed acute embolic infarcts and a lesion on the vertebral artery.

ST-Segment Elevation in the Stress Laboratory

This case report describes a woman in her early 60s who went into cardiac arrest immediately after administration of an echocardiogram contrast agent.

A Clinical Update on MASLD

Metabolic dysfunction–associated steatotic liver disease (MASLD; formerly nonalcoholic fatty liver disease) is a growing cause of chronic liver disease, affecting 25% of the population in the US and 30% of the population globally.1 It is the second leading indication for liver…