Medical Knowledge

Hairy Kidneys and Sclerotic Bone Lesions

A 72-year-old man with a history of polycythemia vera (positive for JAK2 V617F) presented with several months of functional decline and weight loss. An 18F-fluorodeoxyglucose positron emission tomography/computed tomography showed soft tissue infiltrates and sclerosis of the perirenal spaces with…

Social Media and Suicide Risk in Youth

Importance  Youth, parents, educators, and policymakers are concerned about the potential relationship between social media use and negative mental health outcomes, including risk for suicidal thoughts and behaviors. Observations  Current research shows complex and conflicting relationships between social media use and suicide…

Peptic Ulcer Disease – A Review

Importance  In the US, peptic ulcer disease affects 1% of the population and approximately 54 000 patients are admitted to the hospital annually for bleeding peptic ulcers. Observations  Approximately 10% of patients presenting with upper abdominal pain in a primary care setting have…

Ovarian Aging and Fertility

This JAMA Insights discusses ovarian aging and provides strategies to address infertility due to ovarian aging.

Preventing Cannabis Use Among Minors

As more states legalize, decriminalize, or otherwise increase access to cannabis for adult populations, there are also potential health implications for children and adolescents. Maria H. Rahmandar, MD, physician at Northwestern’s Feinberg School of Medicine, explores the risk factors, screening…

Penile Persistent Yellow Plaques With Recurrent Ulcerations

A man in his 30s presented with a painful ulcer on the ventral aspect of the penile shaft that had appeared 3 months before. Physical examination disclosed discrete penile swelling with an indurated yellowish plaque diffusely involving the ventral surface….