Medical Knowledge

Metformin, Maternal Glycemic Control, and Neonatal Hypoglycemia After Antenatal Steroids – A Randomized Clinical Trial

Importance  Although betamethasone reduces complications of prematurity, it can cause maternal hyperglycemia and neonatal hypoglycemia. Metformin effectively treats maternal hyperglycemia and has been shown to decrease neonatal hypoglycemia in women with gestational diabetes. Objective  To evaluate the impact of metformin…

Infection Control for Health Care Professionals

This interactive learning activity provides health care professionals with an overview of evidence-based infection control principles, responsibilities, and practices to ensure the safety of both patients and health care professionals. Learners will explore key regulations, professional standards, and best practices…

Infection Control for Health Care Professionals

This interactive learning activity provides health care professionals with an overview of evidence-based infection control principles, responsibilities, and practices to ensure the safety of both patients and health care professionals. Learners will explore key regulations, professional standards, and best practices…

Perceptions of GLP-1 RA Use for Children With Obesity Among Caregivers With Food Insecurity – A Qualitative Study

Importance  With the approval of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) for pediatric obesity, families are increasingly considering pharmaceutical treatment alongside lifestyle optimization for their children, although how caregivers will make these decisions remains unexplored. This is especially important in…

Barriers to Buprenorphine Initiation in Patients Using Fentanyl

Importance  Anecdotal accounts suggest an increase in problems initiating buprenorphine (BUP) treatment among individuals using illicitly manufactured fentanyl. Limited empirical data illuminate these challenges. Objective  To determine the prevalence of clinician-reported problems initiating BUP treatment among patients using fentanyl and…

Hormonal Contraceptive Use, Stress Disorders, and Cardiovascular and Thrombotic Risk in Women

Importance  Stress and its psychiatric consequences—including depression, anxiety, and posttraumatic stress disorder (PTSD)—are pertinent to women’s cardiovascular health, but research on intersections with relevant sex-specific factors (eg, hormonal contraceptives) is lacking. Objective  To examine whether stress-related psychiatric diagnoses moderate associations…

Angiotensin II–Stimulating Antihypertensive Medications and Dementia-Related Neuropathology

Importance  Antihypertensive medications that stimulate angiotensin II type 2 or 4 receptors (angiotensin II–stimulating medications) may be associated with lower risk of dementia. Objective  To examine associations between cumulative exposure to angiotensin II–stimulating vs angiotensin II–inhibiting antihypertensive medications and neuropathology,…