Medical Knowledge

CNV and Angioid Streaks in Pseudoxanthoma Elasticum

This case report discusses a diagnosis of pseudoxanthoma elasticum in a woman aged 47 years who presented with bilateral blurry vision and a history of intravitreal treatment for choroidal neovascularization (CNV).

When to Use the HINTS Examination in Patients With Dizziness – A Review

Importance  The Head Impulse, Nystagmus, Test of Skew (HINTS) examination is a widely recognized bedside tool for distinguishing peripheral vestibular disorders from central causes, such as stroke, in patients presenting with acute vestibular syndrome. However, despite its introduction in 2009,…

Vaccines for Cancer – A Translational Science Review

Importance  Advances in tumor immunology and vaccine technology are reshaping cancer vaccine development after decades of limited clinical success. More than 2000 immunogenic tumor proteins or antigens have been identified, the types of immune responses required for tumor eradication have…

Management of Colon and Rectal Injuries From Blunt and Penetrating Trauma – Evidence-Based Recommendations From the World Society of Emergency Surgery

Importance  Traumatic colon and rectal injuries generate wide practice variation across diagnosis, operative strategy, technical conduct, and perioperative care. Management has shifted from mandatory fecal diversion toward selective primary repair and physiology-guided reconstruction, but decision-making remains inconsistent. Objective  To develop…

Best Practices for Managing Pseudofolliculitis Barbae – An Expert Consensus Delphi Study

Importance  Pseudofolliculitis barbae (PFB) is a chronic inflammatory disease caused by penetration of a shaved, curved hair shaft into the skin. Standardized recommendations for diagnosing and managing PFB are needed. Objective  To establish expert consensus recommendations outlining best practices for…

Medicolegal Evaluations for Asylum Seekers

This JAMA Insights discusses the importance of medicolegal evaluations for those seeking asylum and encourages clinicians to complete additional training to conduct these evaluations.

Elephantiasic Pretibial Myxedema

This case report describes a man with enlargement of the lower legs with pink nodules and malodor.