Medical Knowledge

Opioid Use and Pain Resolution for Acute Pain Among Opioid-Naive Patients

Importance  High-quality evidence guiding opioid prescribing decisions for acute pain across common diagnoses is lacking. Objective  To describe pain trajectories and patterns of opioid and nonopioid treatment use among individuals who were offered opioids for the treatment of acute pain….

Red Eyes Refractory to Corticosteroids

A 57-year-old man with bilateral red eyes and irritation refractory to topical corticosteroids presents with symmetric yellow conjunctival lesions and progressive systemic nodules and joint pain. What would you do next?

CNV and Angioid Streaks in Pseudoxanthoma Elasticum

This case report discusses a diagnosis of pseudoxanthoma elasticum in a woman aged 47 years who presented with bilateral blurry vision and a history of intravitreal treatment for choroidal neovascularization (CNV).

When to Use the HINTS Examination in Patients With Dizziness – A Review

Importance  The Head Impulse, Nystagmus, Test of Skew (HINTS) examination is a widely recognized bedside tool for distinguishing peripheral vestibular disorders from central causes, such as stroke, in patients presenting with acute vestibular syndrome. However, despite its introduction in 2009,…

Vaccines for Cancer – A Translational Science Review

Importance  Advances in tumor immunology and vaccine technology are reshaping cancer vaccine development after decades of limited clinical success. More than 2000 immunogenic tumor proteins or antigens have been identified, the types of immune responses required for tumor eradication have…