Posted on October 20th, 2026 by Academic Programs
Importance Obesity disproportionately affects low- and middle-income countries, where access to structured, scalable treatment remains limited. Objective To evaluate whether a hybrid-format, intensive lifestyle modification program combined with usual medical care promotes a minimum weight loss of 5% in adults…
Posted on October 20th, 2026 by Academic Programs
Importance Intravenous thrombolysis (IVT) is an established therapy for acute ischemic stroke when administered within 4.5 hours of symptom onset. However, many patients present beyond this window or with unknown onset, and recent randomized clinical trials (RCTs) have evaluated whether…
Posted on October 20th, 2026 by Academic Programs
Importance Most diabetes care is managed in primary care settings, which represent a critical yet underutilized site for continuous glucose monitoring (CGM) adoption. Whether CGM initiation by primary care clinicians improves glycemic outcomes and reduces acute health care utilization remains…
Posted on October 20th, 2026 by Academic Programs
Importance Metastatic prostate cancer (PC) incidence has increased in US men, partly due to changes in prostate-specific antigen (PSA) screening recommendations. However, few studies have examined contemporary PSA screening practices in large US health care systems. Objective To describe and…
Posted on October 20th, 2026 by Academic Programs
Importance High-quality evidence guiding opioid prescribing decisions for acute pain across common diagnoses is lacking. Objective To describe pain trajectories and patterns of opioid and nonopioid treatment use among individuals who were offered opioids for the treatment of acute pain….
Posted on October 20th, 2026 by Academic Programs
Importance Race, ethnicity, and social determinants of health (SDOH) contribute to disparities in diabetes outcomes, particularly hemoglobin A1c (HbA1c). Although continuous glucose monitoring (CGM) improves glycemic management, it remains unclear whether associations persist between SDOH and CGM metrics, as prior…
Posted on October 20th, 2026 by Academic Programs
A 57-year-old man with bilateral red eyes and irritation refractory to topical corticosteroids presents with symmetric yellow conjunctival lesions and progressive systemic nodules and joint pain. What would you do next?
Posted on October 20th, 2026 by Academic Programs
This case report discusses a diagnosis of pseudoxanthoma elasticum in a woman aged 47 years who presented with bilateral blurry vision and a history of intravitreal treatment for choroidal neovascularization (CNV).
Posted on October 20th, 2026 by Academic Programs
Importance The Head Impulse, Nystagmus, Test of Skew (HINTS) examination is a widely recognized bedside tool for distinguishing peripheral vestibular disorders from central causes, such as stroke, in patients presenting with acute vestibular syndrome. However, despite its introduction in 2009,…
Posted on October 19th, 2026 by Academic Programs
Importance Advances in tumor immunology and vaccine technology are reshaping cancer vaccine development after decades of limited clinical success. More than 2000 immunogenic tumor proteins or antigens have been identified, the types of immune responses required for tumor eradication have…