Unilateral Diffuse Pigmentary Retinopathy Associated With Optic Disc Pit
This case report describes a diagnosis of pigmentary retinopathy and optic disc pit in a woman aged 41 years who presented with long-standing decreased vision in the left eye.
Medical Knowledge
An Incarcerated Individual With Weight Loss and Interstitial Pulmonary Infiltrates
A man with HIV had syncopal episodes and hypoxemia after recent exposure to SARS-CoV-2; computed tomography revealed diffuse bilateral pulmonary micronodular opacities, a 2.2-cm nodule in the lingula, and mediastinal and hilar lymphadenopathy. What is the diagnosis and what would…
Unraveling Wavy ST Segments – An Unusual Case of Syncope
This case report describes a patient in their 60s with gastroesophageal reflex disease who presented to the emergency department after loss of consciousness during dinner and daily intermittent chest discomfort.
Introduction to JAMA Climate Change and Health Series
This JAMA Insights introduces the new series on climate change intended to inform readers about the associations between climate change and health.
Segmental Skin Induration in a Boy
An 11-year-old boy presented with progressive unilateral skin hardening on his right thigh and buttock for 7 years. What is your diagnosis?
Diffusely Enhancing Lesions on MRI in DPPX Antibody-Associated Encephalitis
This case report describes a diagnosis of dipeptidyl-peptidase like protein-6 antibody-associated encephalitis in a woman aged 51 years who presented with progressive gait instability, memory impairment, and weight loss.
Real-Time Magnetic Resonance Imaging During Convective Gene Therapy Perfusion of the Brain
This article discusses use of intraoperative MRI in convective gene therapy perfusion.
NAS and NOWS, Part 2
The diagnosis of a substance use or opioid use disorder during pregnancy is linked to complications for the mother, fetus, and newborn. Chronically drug exposed fetuses are at high risk for neonatal abstinence syndrome (NAS) or neonatal opioid withdrawal syndrome…
NAS and NOWS, Part 1
The diagnosis of a substance use or opioid use disorder during pregnancy is linked to complications for the mother, fetus, and newborn. Chronically drug exposed fetuses are at high risk for neonatal abstinence syndrome (NAS) or neonatal opioid withdrawal syndrome…
Diagnostic Safety, Part 1: The Basics
This overview of the discipline of diagnostic safety gives information about the number of diagnostic errors that occur each year in the US. It discusses barriers that make diagnostic errors more likely and presents strategies for making diagnosis safer.
