Brain Organoids in the Study of Psychiatric Disorders
This article discusses the use of brain organoids in modeling the biological mechanisms of psychiatric disease.
ABMS Lifelong Learning CME Activity
Communicating a Diagnosis of Mild Cognitive Impairment or Dementia
This JAMA Insights explores strategies for effectively communicating a diagnosis of mild cognitive impairment or dementia to patients and their care partners.
Waterdrop Lesions in an Adolescent Girl
A teenage girl with atopic dermatitis presented with asymptomatic, skin-colored papules on her abdomen. What is your diagnosis?
It Takes a Village—Association of Women Surgeons’ Comprehensive Initiative for Healthy Surgical Families for Practicing Surgeons
Importance The Association of Women Surgeons is committed to supporting surgical families for practicing surgeons and developing equitable family-friendly guidelines, including support for adequate paid family leave, access to childcare, breastfeeding support, and insurance coverage of fertility preservation and assisted reproductive…
Patient-Reported Outcome Measures and Validation Data Used in Melanoma Research and Routine Practice – A Systematic Review
Importance Patient-reported outcome measures (PROMs) are increasingly used in melanoma research and to guide clinical practice; however, the validation of these PROMs for use in melanoma populations is unknown. Objective To conduct a systematic review and construct an evidence gap map to…
Preserving and Promoting Clinical Trial Representativeness – A Review of Existing Strategies and the Path Forward
Importance Despite major advancements in cardiovascular clinical research, underrepresentation in cardiovascular clinical trials persists, limiting generalizability, access to novel therapies, and equitable care. Observations Policymakers, funding bodies, researchers, and professional societies have increasingly acknowledged the scientific importance of representation of the intended…
A 34-Year-Old With Recurrent Abdominal Pain
A 34-year-old woman had recurrent episodes of crampy, diffuse abdominal pain not relieved by eating or defecation. Laboratory evaluation was unremarkable except for decreased C4 levels; abdominal computed tomography showed jejunal wall edema and ascites; and her father and brother…
A Young Adult With Aggressive Lesions in the Neck
A 20-year-old man presented with bilateral neck masses that gradually increased in size for over 5 months following a red cross tattoo on his anterior neck. What is your diagnosis?
Reporting Guideline for Chatbot Health Advice Studies – The CHART Statement
Importance The rise in chatbot health advice (CHA) studies is accompanied by heterogeneity in reporting standards, impacting their interpretability. Objective To provide reporting recommendations for studies evaluating the performance of generative artificial intelligence (AI)–driven chatbots when summarizing clinical evidence and providing health…
Prostate Cancer Management Simulator
Many factors can influence treatment selection for patients with prostate cancer, including risk stratification strategies, appropriate treatment options for patients with non-metastatic recurrence after maximal pelvic-directed therapy, considerations for selecting treatments for patients with metastatic castration-sensitive and metastatic castration-resistant disease,…
