ABMS Lifelong Learning CME Activity

Obstacles to Biosimilar Acceptance and Uptake in Oncology – A Review

Importance  Biosimilar drugs provide cost-effective yet clinically indistinguishable replications of target drugs. During initial development, this class of biologic medicines was expected to revolutionize pharmaceutical markets; however, following US Food and Drug Administration approval of the first biosimilar drug in 2015,…

Coxsackievirus A6ñInduced Atypical Hand-Foot-Mouth Disease

This case report describes nonblanching, confluent, purpuric macules and patches on the palmoplantar and dorsal finger surfaces and red to grayish papulovesicles on the dorsal hands and feet, limbs, trunk, and face.

Taxane-Induced Cutaneous Toxic Effects

This case report describes dusky red to violaceous lesions with desquamation on the wrists and dorsal surface of both hands and near the Achilles tendon that occurred after intravenous paclitaxel treatment for invasive ductal carcinoma of the breast.

Immunotherapy for a Choroidal Pigmented Lesion

A 51-year-old male with a a history of BRAF V600 E mutation-positive, superficial spreading-type cutaneous melanoma on the chest with metastasis to a sentinel lymph node had a 4-week history of redness and swelling of the right temporal bulbar conjunctiva…

Episodic Upper Eyelid Edema in an African American Patient

An African American patient in their 60s with a history of monoclonal gammopathy of unknown significance presents to the oculoplastic service for intermittent, bilateral upper eyelid swelling and pain for 2 years. Examination reveals hyperpigmented, spongy eyelid edema with redundant…

Chronic Chagas Disease in the US

This JAMA Insights provides recommendations for Chagas disease screening, diagnosis, and management in the US

Filamentous RPE Hyperplasia in Combined Hamartoma of the Retina and RPE

This case report describes a diagnosis of combined hamartoma of the retina and retinal pigment epithelium (RPE) with filamentous RPE hyperplasia in a female child with a history of amblyopia, myopia, and exotropia of the affected eye.

Fluorescein Angiography of Floating Retinal Veins

This case report describes a diagnosis of floating retinal veins in a patient aged 4 years with a history of stage 2 familial exudative vitreoretinopathy.

Vitreopapillary Traction in Stickler Type IV COL9A1

This case report describes a woman aged 43 years with Stickler syndrome and bilateral vitreopapillary traction who presented with shadows and ghosting of vision in both eyes.