Importance Immunoglobulin G4 (IgG4)–related disease is an increasingly recognized fibroinflammatory condition that can involve multiple organs, including the pachymeninges. The understanding of IgG4-related pachymeningitis (IgG4-RP) remains limited because of its rarity and the predominance of knowledge derived from case reports and…
Importance Polycythemia vera (PV), a myeloproliferative neoplasm characterized by an increased red blood cell mass and increased risk of thrombosis, affects approximately 65 000 people in the US, with an annual incidence of 0.5 to 4.0 cases per 100 000 persons. Observations Erythrocytosis (hemoglobin…
To provide optimal patient care, clinicians need to be well informed about the latest clinical research updates and how these advances compare to the current clinical practice standards. This activity will allow for self-directed online learning to assist in the…
Ambulatory surgery is growing in popularity among physicians and patients. While it can be convenient and less expensive, ambulatory surgery also has risks. The risks oblige all those involved with ambulatory surgeries to make effective decisions about what procedures to…
This activity discusses ways systems factors (flaws or weaknesses in organizational systems of care) can sabotage correct diagnoses. Think about a primary care practice with no specific policy for checking if patients actually go to recommended tests and consults, which…
In medicine, the formulation of a differential diagnosis is fundamental to the diagnostic reasoning process. It is less likely to find documentation of a differential diagnosis in cases that have diagnostic errors. This activity presents strategies to fortify the differential…
BMJ Best Practice is a clinical decision support tool that supports healthcare professionals in diagnosing and managing patients. It is a knowledge resource that is continually updated, evidence-based, actionable and practical. It helps healthcare professionals fill gaps in their medical…
This JAMA Insights explores how clinicians can use the harm reduction communication framework to engage with patients who have opioid use disorder, which could help prevent overdose and other substance use related harms.
This JAMA Insights explores harm reduction strategies for people who use drugs and the clinicians who treat them to help reduce the risk of unintentional drug overdose and infection.
Importance The results of small studies suggest that off-label use of low-dose oral minoxidil (LDOM) may be safe and effective for patients with hair loss, but larger trials and standardized guidelines are lacking. Objective To create an expert consensus statement for LDOM…
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