ABMS Lifelong Learning CME Activity

Five Things Clinicians Need to Know About Zoonotic Viral Spillover and Spillback

Since the 1990s, multiple infectious diseases have “spilled over” from nonhuman animals to infect humans and cause significant global morbidity and mortality. Despite efforts to detect and respond to such threats, surveillance and mitigation efforts have been criticized as ineffective….

How One Health Instrumentalizes Nonhuman Animals

This article interrogates anthropocentrism and nonhuman animal instrumentalization in One Health (OH). It argues that OH’s approach to human health and zoonosis focuses too narrowly on furthering certain human interests at the expense of nonhuman animals, which is not sustainable,…

Building CRISPR Gene Therapies for the Central Nervous System – A Review

Importance  Gene editing using clustered regularly interspaced short palindromic repeats (CRISPR) holds the promise to arrest or cure monogenic disease if it can be determined which genetic change to create without inducing unintended cellular dysfunction and how to deliver this technology…

A 51-Year-Old Woman With Abnormal Corpus Callosum Signal

A 51-year-old woman presented with a 2-year history of progressive memory loss and left limb numbness. Imaging showed multifocal restricted diffusion in the corpus callosum and diffuse subcortical white matter hyperintensities and corpus callosum atrophy. What is your diagnosis?

Strategies to Improve Medical Communication

This JAMA Insights summarizes strategies for effective medical communication, with considerations for the message delivered, the messenger source, and the social context.

Anterior Chamber Snowflake After Keratoplasty

A 62-year-old woman presented with painless vision reduction and eye redness in the right eye for a week. Nine months after keratoplasty, she presented with diffuse tiny nodules all over the iris and a dense opacity in the anterior vitreous…

Sudden ST-Segment Changes in a Critically Ill Patient

A patient in his mid-60s underwent bilateral orthotopic lung transplant and is later hospitalized for sepsis from pneumonia complicated by acute transplant rejection, without any cardiac symptoms. He develops severe acute respiratory distress syndrome requiring intubation and paralysis. Electrocardiography shows…