When Dysuria Is More Than Just a Urinary Tract Infection – A Teachable Moment
This Teachable Moment describes a 66-year-old woman with mild dysuria, vulvar discomfort, and recurrent urinary tract infections.
Journal-based
CAR T Cells and T-Cell Therapies for Cancer – A Translational Science Review
Importance Chimeric antigen receptor (CAR) T cells are T lymphocytes that are genetically engineered to express a synthetic receptor that recognizes a tumor cell surface antigen and causes the T cell to kill the tumor cell. CAR T treatments improve overall…
Guidelines for the Prevention, Diagnosis, and Management of Urinary Tract Infections in Pediatrics and Adults – A WikiGuidelines Group Consensus Statement
Importance Traditional approaches to practice guidelines frequently result in dissociation between strength of recommendation and quality of evidence. Objective To create a clinical guideline for the diagnosis and management of urinary tract infections that addresses the gap between the evidence and recommendation…
A Young Woman With Headaches and Peripheral Vision Loss
A 30-year-old nulliparous woman with obesity and history of migraines and depression had 1 month of daily headaches, transient bilateral visual blurring, persistent vision loss in the temporal region of one eye, pulsatile tinnitus, and mild bilateral papilledema. What is…
Madelung Disease
This case report describes nontender, soft, and mobile tissue proliferations involving the anterior, lateral, and posterior neck spaces and diffuse, nonencapsulated soft tissue masses that were widely distributed across superficial and deep fascial spaces.
Postmarketing Surveillance of Inferior Vena Cava Filters Among US Medicare Beneficiaries – The SAFE-IVC Study
Importance Inferior vena cava filters (IVCFs) are commonly used to prevent pulmonary embolism in selected clinical scenarios, despite limited evidence to support their use. Current recommendations from professional societies and the US Food and Drug Administration endorse timely IVCF retrieval when…
Working With Medical Interpreters
This JAMA Insights discusses the important role that interpreters play in facilitating communication between patients with limited English-language proficiency and their health care team and provides steps that can be taken to improve communication with remote interpreters for patients.
Bilateral Perifoveal Atrophy in a 46-Year-Old Woman
A 46-year-old woman is referred for a second opinion with recent onset of suspected seizures and imbalance. Fundus examination revealed bilateral discrete perifoveal circular areas of atrophy. What would you do next?
Calcific Aortic Stenosis – A Review
Importance Calcific aortic stenosis (AS) restricts the aortic valve opening during systole due to calcification and fibrosis of either a congenital bicuspid or a normal trileaflet aortic valve. In the US, AS affects 1% to 2% of adults older than 65…
Imaging in Diagnosis and Active Surveillance for Prostate Cancer – A Review
Importance Active surveillance (AS) has become an increasingly important option for managing low-risk and select intermediate-risk prostate cancer. Although imaging, particularly multiparametric magnetic resonance imaging (mpMRI), has emerged in the prebiopsy pathway for the diagnosis of prostate cancer, the role of…
