Journal-based

Providing a Safe Pregnancy Experience for Surgeons – A Review

Importance  Childbearing has been a particular barrier to successful recruitment and retention of women in surgery. Pregnant surgeons are more likely to have major pregnancy complications, such as preterm delivery, intrauterine growth restriction, infertility, and miscarriage, compared with nonsurgeons. The average…

Sudden Hearing Loss and Vertigo After Sinus Occlusion

A 67-year-old patient presented with persistent vertigo and pulsatile tinnitus in the left ear for the past 3 months, and 5 days after treatment he experienced acute hearing loss of the left ear and vertigo. What is your diagnosis?

Enhancing Postmarketing Surveillance of Medical Products With Large Language Models

Importance  The Sentinel System is a key component of the US Food and Drug Administration (FDA) postmarketing safety surveillance commitment and uses clinical health care data to conduct analyses to inform drug labeling and safety communications, FDA advisory committee meetings, and…

Whole-of-Life Inclusion in Bayesian Adaptive Platform Clinical Trials

Importance  There is a recognized unmet need for clinical trials to provide evidence-informed care for infants, children and adolescents. This Special Communication outlines the capacity of 3 distinct trial design strategies, sequential, parallel, and a unified adult-pediatric bayesian adaptive design, to…

Tombstone Pattern Electrocardiogram in a Young Woman

A woman in her mid-20s presented with acute fever, chest pain, and exertional dyspnea. Electrocardiogram results showed sinus tachycardia, QRS widening, low-voltage complexes, and ST-segment elevation. What would you do next?

A 45-Year-Old With Multiple Skin Lesions on Sun-Protected Areas of the Body

A patient had multiple erythematous macules and patches on the trunk, hyperpigmented patches on the intergluteal cleft and subgluteal fold, and poikiloderma in the axillae; results of laboratory testing, including antinuclear antibody test, were unremarkable. What is the diagnosis and…