Wearable Intraoperative Augmented Reality for Surgery
This Surgical Innovation explores the potential that wearable augmented reality devices have for improving intraoperative imaging, patient outcomes, and surgical workflows.
Journal-based
Eladocagene Exuparvovec for Aromatic L-Amino Acid Decarboxylase Deficiency
This JAMA Insights discusses the US Food and Drug Administration approval of Kebilidi, eladocagene exuparvovec, for the treatment of aromatic L-amino acid decarboxylase deficiency in adult and pediatric patients.
Exercise-Induced Dyspnea in an Older Woman With a History of Coronary Artery Disease
An older woman with a history of coronary artery disease presents with dyspnea upon exertion. A transthoracic echocardiogram reveals severe mitral regurgitation, and an electrocardiogram reveals sinus tachycardia with left bundle branch block. What would you do next?
A Firm Pigmented Plaque on the Forearm of a Child
A 12-year-old boy was referred to the dermatology clinic with a nonprogressive hyperpigmented and indurated plaque on his right forearm for 5 years. What is your diagnosis?
Expectancy Effects, Failure of Blinding Integrity, and Placebo Response in Trials of Treatments for Psychiatric Disorders – A Narrative Review
Importance Expectancy effects are significant confounding factors in psychiatric randomized clinical trials (RCTs), potentially affecting the interpretation of study results. This narrative review is the first, to our knowledge, to explore the relationship between expectancy effects, compromised blinding integrity, and the…
Bilateral Retinal Detachments in a Previously Healthy 19-Year-Old
A 19-year-old man was referred for evaluation of bilateral retinal detachments. Imaging demonstrated subretinal and intraretinal fluid in the macula of both eyes with no choroidal masses. What would you do next?
Point-of-Care Ultrasound in Sepsis and Septic Shock
This JAMA Insights explores the use of portable point-of-care ultrasound and focused cardiac ultrasound imaging in the diagnosis and treatment of patients with sepsis and septic shock in the emergency department and intensive care unit.
Belly Dancerís Dyskinesia Following Acute Corpus Callosum Infarction
This case report describes a patient with spontaneous, arrhythmic, spasmodic contractions of the abdominal muscles whose imaging confirmed involvement of the genu, body, and splenium of the corpus callosum.
Chronic Myeloid Leukemia – A Review
Importance Chronic myeloid leukemia (CML) has an annual incidence of 2 cases per 100 000 people and is newly diagnosed in approximately 9300 individuals per year in the US. Approximately 150 000 people in the US and 5 million worldwide have CML. Observations Chronic…
Negotiating With Patients About Tests, Referrals, and Treatments
This JAMA Insights discusses how physicians can engage in successful clinical negotiation if a patient requests a test or treatment that is deemed inappropriate, potentially harmful, or low-value.
