Diagnosis and Treatment of Obstructive Sleep Apnea
This Clinical Insights discusses the role primary care clinicians have in screening, diagnostic testing, and treatment of patients with obstructive sleep apnea.
Journal-based
Polymyositis Masking Statin-Induced Necrotizing Autoimmune Myopathy – A Teachable Moment
This case report describes a patient in their 70s with treatment-resistant polymyositis, coronary artery disease, bare-metal stent placement, 3 months of fatigue, and worsening proximal muscle weakness.
Hemorrhoidal Disease – A Review
Importance Hemorrhoidal disease, pathology of the tissue lining of the anal canal, affects approximately 10 million individuals in the US. Hemorrhoidal disease may impair quality of life due to bleeding, pain, anal irritation, and tissue prolapse. Observations Hemorrhoids are classified as internal,…
Stapokibart for Severe Uncontrolled Chronic Rhinosinusitis With Nasal Polyps – The CROWNS-2 Randomized Clinical Trial
Importance Chronic rhinosinusitis with nasal polyps causes severe symptoms and impaired quality of life. Stapokibart is a novel monoclonal antibody that targets interleukin 4Rα. Objective To assess the efficacy and safety of stapokibart as an add-on treatment to intranasal corticosteroids in patients…
Treatment of Atopic Dermatitis
This JAMA Insights explores topical treatments and systemic therapies for atopic dermatitis, the most common chronic inflammatory skin condition globally.
Bilateral Intravitreal Injection of Methylprednisolone
This case report discusses surgical management of retinal necrosis after unintentional injection of methylprednisolone into the vitreous cavity of a patient with nonarteritic anterior ischemic optic neuropathy.
Leopard Spots in Antiglomerular Basement Membrane Disease
This case report discusses a diagnosis of Goodpasture syndrome in a patient aged 56 years who presented with 4 months of blurred vision and bilateral leopard spots on fundus examination.
Hyphema and Yellow Floaters in a Patient With Hyperlipidemia
This case report discusses the management of pain and elevated intraocular pressure in patient with persistent hypercholesterolemia who experienced penetrating ocular trauma 20 years prior.
Retinal Arteriolar Emboli From Facial Triamcinolone Injection
This case report describes a diagnosis of retinal arteriolar emboli secondary to a facial triamcinolone injection for allergic dermatitis in a male patient aged 45 years.
High-Dose Buprenorphine Treatment in the Setting of Fentanyl
Importance The emergence of fentanyl in the setting of the US opioid crisis demands reconsideration of clinical approaches to buprenorphine initiation for patients with opioid use disorder (OUD), with the rationale that fentanyl’s unique pharmacology leads to a greater risk of…
