JAMA Pediatrics

Suicide Interventions for Youths – A Systematic Review

Importance  Suicide is a leading cause of death among young people and an escalating public health crisis. Objective  To assess the effectiveness and harms of available treatments for suicidal thoughts and behaviors among youths at heightened risk for suicide. Evidence Review  A systematic…

Medicaid and the Promise for Cure

Importance  Cell and gene therapies are revolutionizing the treatment landscape for children and adults with rare diseases and can be life-changing for patients and their families. Successful implementation of these new therapies into clinical practice depends on their accessibility and affordability,…

Disseminated Pseudovesicles in an Immunocompromised Patient

A 41-year-old immunocompromised man presented to the intensive care unit with neutropenic fevers, and after a 1-week stay, developed oral ulcers and tender, diffuse, erythematous pseudovesicular papules, many umbilicated, on the face, trunk, and extremities. What is your diagnosis?

About Whom Are We Talking When We Use Intellectual and Developmental Disabilities?

Importance  Communicating clearly about who is included in a population group is a critical element to effective dissemination and knowledge transfer. This narrative review highlights the inconsistency as it relates to communicating about individuals with intellectual disability (ID) and developmental disability…

Whole-of-Life Inclusion in Bayesian Adaptive Platform Clinical Trials

Importance  There is a recognized unmet need for clinical trials to provide evidence-informed care for infants, children and adolescents. This Special Communication outlines the capacity of 3 distinct trial design strategies, sequential, parallel, and a unified adult-pediatric bayesian adaptive design, to…