Changing Rapid Wide Complex Tachycardia in a Middle-Aged Man
This case report describes a man in his 40s who presented to the emergency department with reported palpitation and breathlessness for the preceding 2 hours.
JAMA Internal Medicine
Screening for Syphilis Infection in Persons With Moth-Eaten Alopecia
This Teachable Moment discusses the importance of recognizing the clinical clue of moth-eaten alopecia for secondary syphilis.
Diagnosis and Treatment of Obstructive Sleep Apnea
This Clinical Insights discusses the role primary care clinicians have in screening, diagnostic testing, and treatment of patients with obstructive sleep apnea.
Polymyositis Masking Statin-Induced Necrotizing Autoimmune Myopathy – A Teachable Moment
This case report describes a patient in their 70s with treatment-resistant polymyositis, coronary artery disease, bare-metal stent placement, 3 months of fatigue, and worsening proximal muscle weakness.
Decoding South African Flag Sign—When Lead V2 Speaks Volumes
This case report describes a man in his 60s with South African flag sign on electrocardiography.
A Mysterious ST Elevation
This case report describes the electrocardiogram of a patient in their 70s with palpitations, fatigue, and dyspnea taking a combination of an immune checkpoint inhibitor and chemotherapy for lung cancer.
Evaluation of Hypercortisolism in Mild Autonomous Cortisol Secretion
This Teachable Moment describes a woman in her early 50s with obesity, hypertension, and type 2 diabetes who presented to the endocrine clinic for evaluation of an incidental left adrenal nodule.
Projected Lifetime Cancer Risks From Current Computed Tomography Imaging
Importance Approximately 93 million computed tomography (CT) examinations are performed on 62 million patients annually in the United States, and ionizing radiation from CT is a known carcinogen. Objective To project the number of future lifetime cancers in the US population associated…
Semaglutide vs Tirzepatide for Weight Loss in Adults With Overweight or Obesity
Importance Although tirzepatide and semaglutide were shown to reduce weight in randomized clinical trials, data from head-to-head comparisons in populations with overweight or obesity are not yet available. Objective To compare on-treatment weight loss and rates of gastrointestinal adverse events (AEs) among…
Targeting MASLD and MASH in the US Hispanic/Latino Population – A Review
Importance The prevalence of metabolic dysfunction–associated steatotic liver disease (MASLD) in the US is highest among Hispanic/Latino individuals. Their risk of developing metabolic dysfunction–associated steatohepatitis (MASH) with fibrosis, cirrhosis with progression to hepatocellular carcinoma and need for liver transplant, and death…
