Lesioning the BrainóFrom Serendipity to Science
This case report describes use of high-intensity focused ultrasound as a method to create spatially precise thermal lesions in the brain without a craniotomy.
Medical Knowledge
AMA STEPSForward – A Systematic Approach to Reducing EHR Inbox Burden
This toolkit will help you develop and execute tactics to reduce the work burden of the EHR inbox, which disproportionately impacts physicians.
A Patient With Proteinuria, Myalgias, and Decreased Pigmentation of Facial Skin
A patient had bilateral leg edema, insomnia, myalgias, paresthesias in the fingertips, lighter pigmentation of the facial skin compared with other areas of the body, proteinuria, and an elevated creatinine level. What is the diagnosis and what would you do…
Standardizing Retrospective Observational Research in Cutaneous Squamous Cell Carcinoma – Expert Panel Guidelines from ITSCC
Importance Cutaneous squamous cell carcinoma (CSCC) is the second most common malignant disease in the US. Although it typically carries a good prognosis, a subset of CSCCs are highly aggressive, carrying regional and distant metastatic potential. Due to its high incidence,…
Management of Patients With Chronic Coronary Disease
This JAMA Clinical Guidelines Synopsis summarizes the 2023 American Heart Association (AHA)/American College of Cardiology (ACC) guideline on management of patients with chronic coronary disease.
Exanthematous Eruption in a Patient With Known Chronic Graft-vs-Host Disease and Recent Measles Vaccination
A man in his 40s with a history of allogeneic stem cell transplant for diffuse large B-cell lymphoma and Graft-vs-host disease (GVHD) presented with a generalized eruption 1 week after receiving a measles, mumps, and rubella vaccination. What is your…
BRCA1, BRCA2, and Associated Cancer Risks and Management for Male Patients – A Review
Importance Half of all carriers of inherited cancer-predisposing variants in BRCA1 and BRCA2 are male, but the implications for their health are underrecognized compared to female individuals. Germline variants in BRCA1 and BRCA2 (also known as pathogenic or likely pathogenic variants, referred to here as BRCA1/2 PVs) are well known to…
Congenital Cutaneous Sinus at the Sternoclavicular Joint
A 32-year-old female patient presented with chronic discharging sinus with recurrent infection at the left sternoclavicular joint. What is your diagnosis?
Heat-Related Illness in Athletes
This JAMA Insights discusses heat-related illness in athletes, including risk factors, prevention, symptoms, and management.
Anterior Cruciate Ligament Injuries in Female Athletes
This JAMA Insights discusses anterior cruciate ligament (ACL) injuries in female athletes, including modifiable and nonmodifiable sex-based risk factors and the implementation of ACL injury prevention programs.
