Medical Knowledge

Branch Retinal Artery Occlusion in an Adolescent Male

A 17-year-old male with an unremarkable medical history presented with 2 days of painless blurred vision in the right eye. Three weeks prior, he was admitted with fever, myalgias, hepatosplenomegaly, lymphadenopathy, and truncal rash. What would you do next?

Differences in Drug Shortages in the US and Canada

Importance  Drug shortages are a persistent public health issue that increased during the COVID-19 pandemic. Both the US and Canada follow similar regulatory standards and require reporting of drug-related supply chain issues that may result in shortages. However, it is unknown…

Government Obligations and the Negative Right to a Healthy Urban Environment

Urban development often generates noise and light pollution, reduces green space, produces heat islands, and increases population density that can exacerbate crime, disease transmission, anxiety, and stress. This article argues that individuals and communities have rights to not have their…

Ethics Talk: Therapeutic Music and Peace in Health Care

This activity is comprised of five multiple-choice questions based on the content of an AMA Journal of Ethics podcast about therapeutic music and peace in health care. The featured guests are Daniel Levitin, PhD, neuroscientist, cognitive psychologist, and author of…

CAR T Cells and T-Cell Therapies for Cancer – A Translational Science Review

Importance  Chimeric antigen receptor (CAR) T cells are T lymphocytes that are genetically engineered to express a synthetic receptor that recognizes a tumor cell surface antigen and causes the T cell to kill the tumor cell. CAR T treatments improve overall…

Guidelines for the Prevention, Diagnosis, and Management of Urinary Tract Infections in Pediatrics and Adults – A WikiGuidelines Group Consensus Statement

Importance  Traditional approaches to practice guidelines frequently result in dissociation between strength of recommendation and quality of evidence. Objective  To create a clinical guideline for the diagnosis and management of urinary tract infections that addresses the gap between the evidence and recommendation…