Medical Knowledge

Preserving and Promoting Clinical Trial Representativeness – A Review of Existing Strategies and the Path Forward

Importance  Despite major advancements in cardiovascular clinical research, underrepresentation in cardiovascular clinical trials persists, limiting generalizability, access to novel therapies, and equitable care. Observations  Policymakers, funding bodies, researchers, and professional societies have increasingly acknowledged the scientific importance of representation of the intended…

A 34-Year-Old With Recurrent Abdominal Pain

A 34-year-old woman had recurrent episodes of crampy, diffuse abdominal pain not relieved by eating or defecation. Laboratory evaluation was unremarkable except for decreased C4 levels; abdominal computed tomography showed jejunal wall edema and ascites; and her father and brother…

A Young Adult With Aggressive Lesions in the Neck

A 20-year-old man presented with bilateral neck masses that gradually increased in size for over 5 months following a red cross tattoo on his anterior neck. What is your diagnosis?

Reporting Guideline for Chatbot Health Advice Studies – The CHART Statement

Importance  The rise in chatbot health advice (CHA) studies is accompanied by heterogeneity in reporting standards, impacting their interpretability. Objective  To provide reporting recommendations for studies evaluating the performance of generative artificial intelligence (AI)–driven chatbots when summarizing clinical evidence and providing health…

Prostate Cancer Management Simulator

Many factors can influence treatment selection for patients with prostate cancer, including risk stratification strategies, appropriate treatment options for patients with non-metastatic recurrence after maximal pelvic-directed therapy, considerations for selecting treatments for patients with metastatic castration-sensitive and metastatic castration-resistant disease,…

Healthy Weight Missouri – Medical Providers

These trainings review guideline-based recommendations for evaluation and treatment of children and adults with obesity. Included are practical tips for talking about weight with patients, assessing eating, activity, sleep and other related habits, screening for comorbidities, and engaging in shared…

Beyond the Scale Personalized Care for Obesity in Adults & Adolescents

More effective treatment options for Missouri adults and youth with obesity are available than ever before. This training will familiarize healthcare professionals with intensive/family-based behavioral treatment and medication therapy for patients with obesity. The session will review health behavior changes…

Clinical Perspectives on the Pathophysiology of Facial Synkinesis – A Narrative Review

Importance  Facial synkinesis refers to pathologic cocontraction and baseline hypertonicity of muscles innervated by the facial nerve, commonly attributed to the aberrant regeneration of nerve fibers following injury. The pathomechanism and optimal treatment of facial synkinesis remain unclear. The goal of…