Circular Necrotic Yellow-Red Plaque on the Chest
A man in his 40s presents with a progressively enlarging yellow-red plaque on the chest with multiple central yellow papules, open comedones, and telangiectasia. What is your diagnosis?
ABMS Lifelong Learning CME Activity
Subungual Amelanotic Melanoma
This case report describes a light pink plaque underneath an atrophied and broken nail plate that was surrounded by depigmentation.
Coronary Artery Calcium Testing—Too Early, Too Late, Too Often
Importance Traditional risk factors, enhancing factors, and risk scores help clinicians assess atherosclerotic cardiovascular disease (ASCVD) risk for primary prevention. The latest cholesterol guidelines suggest measuring coronary artery calcium (CAC) score by computed tomography (CT) in those at intermediate risk when…
Conjunctival Nodule in a Female With Ulcerative Colitis
A 69-year-old woman developed a nodule in her left eye and reported bilateral eye fatigue, burning, and irritation. The patient had ulcerative colitis, type 2 diabetes, gastroesophageal reflux disease, hypertension, and glaucoma in her right eye. What is your diagnosis?
Eating Disorders – A Review
Importance Eating disorders are characterized by disturbances in eating behavior and occur worldwide, with a lifetime prevalence of 2% to 5%. They are more common among females than males and may be associated with medical and psychiatric complications, impaired functioning, and…
Current Progress and Future Directions of Immunotherapy in Head and Neck Squamous Cell Carcinoma – A Narrative Review
Importance For decades, the 3 therapeutic pillars for head and neck squamous cell carcinoma (HNSCC) have been radiation therapy, chemotherapy, and surgery. In recent years, a fourth pillar, immunotherapy, has shifted the existing paradigm of oncologic care by improving survival outcomes….
Newborn Screening for Sickle Cell Disease and Thalassemia
Importance Hemoglobin disorders are a considerable public health issue with more than 500 000 affected infants born annually worldwide. First introduced in the 1970s, newborn screening (NBS) for sickle cell disease (SCD) was included in the Recommended Uniform Screening Panel (RUSP) in…
An Evidence-Based Approach to Climate Change and Health
This JAMA Insights discusses the need to fully assimilate evidence from observed and projected effects of climate change on health and invest in developing and implementing effective health protection from preventable climate-sensitive conditions.
What Is a Stepped-Wedge Cluster Randomized Trial?
This Guide to Statistics and Methods describes design, interpretation, and examples of a stepped-wedge cluster randomized trial.
Cerebral White Matter Abnormality Features of Encephalitis Caused by Angiostrongylus cantonensis
This case report describes cerebral white matter abnormalities from encephalitis caused by Angiostrongylus cantonensis in a 60-year-old woman.
