JAMA Otolaryngology – Head & Neck Surgery

Odynophagia With a Glottic Mass and Diffuse Lymphadenopathy

A 34-year-old man with no significant medical history presented with progressive dysphonia, dysphagia, and an infiltrative laryngeal mass that remained nondiagnostic on multiple biopsies. What was the diagnosis?

Persistent Epiglottic Swelling With Ulceration

A male patient in his 60s with a foreign-body sensation in the throat was treated for acute epiglottitis, but supraglottic swelling persisted. What is your diagnosis?

A Patient With Tooth Mobility and a Maxillary Lesion

A 41-year-old patient was referred to the oral and maxillofacial surgery department with slight mobility of the upper right canine with occasional swelling. What is your diagnosis?

Refractory Progressive Facial Asymmetry in a Young Woman

A 20-year-old woman had, since age 8 years, a lesion on the left side of her face that had slowly progressed over 12 years, causing facial asymmetry. Examination revealed an ill-defined soft tissue mask, and imaging showed bone involvement. What…

Rapidly Enlarging Facial Mass Following SARS-CoV-2 Infection

A female adolescent presented with a 1-month history of a rapidly enlarging, vegetative mass on her right cheek after a symptomatic SARS-CoV-2 infection with high fever. What is your diagnosis?

Radiomics in Otolaryngology–Head and Neck Surgery – A Review

Importance  Radiomics is a field that establishes associations between quantifiable imaging biomarkers and histopathological characteristics or clinical outcomes. Radiomics holds particular promise in otolaryngology given anatomic intricacies, diverse pathologies, and many commonplace imaging modalities. Radiomics applications span diagnostic classifiers, long-term prognosticators,…

Large Language Models and Otolaryngology – A Review

Importance  Large language models (LLMs), a rapidly advancing domain of artificial intelligence (AI), are poised to transform administrative, clinical, and research paradigms. Although adoption across medicine has accelerated, otolaryngology represents only a fraction of this progress compared with other specialties. This…

Head and Neck Cancer Salvage Surgery in the Era of Immunotherapy and Beyond – A Review

Importance  Head and neck squamous cell carcinoma (HNSCC) is a challenging malignant condition associated with significant morbidity and mortality. Salvage surgery, in addition to other available treatment modalities, constitutes an important therapeutic intervention for locoregionally recurrent HNSCC, offering the potential for…

Optimizing Otolaryngology Training Through Sports Psychology—The Mental Game

Importance  Otolaryngologists share many important characteristics with elite athletes, including specialized skill development through rigorous training, complex motor activity under pressure, and performance with high stakes. Applied sports psychology emerged to help athletes develop the intangible skills necessary to succeed in…