Activity ID



April 19, 2021

Format Type


CME Credit



CME Provider

American College of Physicians


The SAFE Opioid Course provides guidance that is essential for safe and effective pain management when prescribing extended-release (ER) and long-acting (LA) opioids. It is critical to recognize best practices for how to start to therapy with ER/LA, how to provide therapy, how to end therapy, and what to do in between. Evidence-based tools are required for screening at-risk patients and for monitoring adherence to prescribed ER/LA opioids. Proven methods to counsel patients on ER/LA opioids and to achieve positive outcomes need to be employed. Comprehensive information is also essential on ER/LA-opioids as a drug class. This recorded course will provide clinical insights from the SAFE Opioid Prescribing Blueprint.

This activity features six half-hour educational segments, plus questions and answers facilitated by expert faculty.

This SAFE Opioid Course—a Risk Evaluation and Mitigation Strategy (REMS) activity—allows you to leave the site and return to complete the course in segments, depending on your schedule. To earn CME credit and ABIM Medical Knowledge MOC points, you must complete all six modules and correctly answer at least seven of 12 medical knowledge questions.

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ABMS Member Board Approvals by Type
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NOTE: If a Member Board has not deemed this activity for MOC approval as an accredited CME activity, this activity may count toward an ABMS Member Board’s general CME requirement. Please refer directly to your Member Board’s MOC Part II Lifelong Learning and Self-Assessment Program Requirements.

Educational Objectives

1.Implement patient assessment strategies, including tools to assess risk of abuse, misuse, or addiction when prescribing extended-release (ER/LA) opioids.
2.Employ approaches to safely initiate therapy, modify dose, and discontinue ER/LA opioids.
3.Monitor patients by evaluating treatment goals and implementing periodic urine drug testing (UDT).
4.Employ patient education strategies about the safe use of ER/LA opioids.
5.Identify similarities and differences among ER/LA opioids.


REMS, Opioid Epidemic, Safe Opioid Prescribing, ER/LA


Medical Knowledge

CME Credit Type

AMA PRA Category 1 Credit

Opioid REMS

This educational activity is supported by an independent educational grant from the Extended-Release/Long-Acting Opioid Analgesic REMS Program Companies.

MIPS Approved

This activity qualifies for the CMS Merit-based Incentive Payment System (MIPS), where you can earn a performance-based payment adjustment to your Medicare payment

Practice Setting

Academic Medicine, Inpatient, Outpatient, Physician Executives, Physician Scientists, Rural, Urban, VA/Military

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The information provided on this page is subject to change. Please refer to the CME Provider’s website to confirm the most current information.